Co-director-injected Rejuran at Myeongdong 6F · salmon-DNA polynucleotide skin remodeling · Book consultation
Rejuran salmon-DNA polynucleotide skin booster injection at Kind Global Clinic Myeongdong
Skin Booster · Regenerative Injection · Myeongdong 6F

Rejuran in Myeongdong, Seoul

KFDA-cleared salmon-DNA polynucleotide (PN/PDRN) skin booster injected intradermally to rebuild dermal collagen, refine pore appearance, and restore elasticity — Korean-origin regenerative protocol delivered personally by Dr. Lee Wonjin or Dr. Lee Kangin with same-physician continuity from consultation through the four-session cycle.

3-4
Sessions, 4-wk apart
2cc
Per full-face session
1-2d
Pinprick downtime
Quick Answer

What is Rejuran at Kind Global Clinic?

Rejuran at Kind Global Clinic Myeongdong is a KFDA-cleared salmon-DNA polynucleotide intradermal skin booster that rebuilds dermal collagen, refines pore appearance and restores elasticity across a four-week-interval three to four-session cycle, performed personally by our two co-directors.

Rejuran is a regenerative skin booster manufactured by Pharma Research in Korea, formulated from purified polynucleotide (PN) and polydeoxyribonucleotide (PDRN) fragments extracted from salmon-sperm DNA. The molecules are biologically homologous to human DNA fragments, which is why the injected polynucleotide is read by dermal fibroblasts as a regenerative signal — driving collagen synthesis, capillary remodeling, and extracellular-matrix rebuilding rather than acting as a volume filler.

The standard Rejuran protocol uses 2 cubic centimeters per full-face session, distributed across the dermis as 50 to 80 small intradermal aliquots in a grid microneedling-style injection pattern. Three to four sessions are scheduled four weeks apart, with the cycle then maintained every 6 to 12 months once dermal remodeling is established. The Kind Global Myeongdong lineup includes Rejuran Healer (2cc, standard full-face), Rejuran Hb (1cc, hydration-enhanced variant), Rejuran Eye (1cc, fine periorbital formulation), Kind Premium Rejuran (4cc package), and Lip Rejuran Hb (1cc, perioral).

Both co-directors personally inject every Rejuran patient — no nurse delegation, no junior-doctor rotation. Brand, lot number, total cubic centimeter count per session, total injection points, and dermashine-vs-manual injection technique are recorded on each patient's chart at the time of injection. Compared with hyaluronic-acid bio-remodelers like <a href="/profhilo-myeongdong-seoul-korea/">Profhilo</a> or cocktail boosters like <a href="/mesotherapy-myeongdong-seoul-korea/">Mesotherapy</a>, Rejuran is the regenerative protocol with the strongest Korean dermatology literature on skin quality, pore refinement and post-acne texture.

Who is this for?

Who is Rejuran for?

For

  • Patients with enlarged pores, post-acne texture, fine crepey lines, and loss of dermal elasticity rather than volume deficit
  • Late-20s to 50s patients seeking regenerative dermal remodeling without filler or muscle-relaxant components
  • Patients with dull, dehydrated, sun-damaged skin where the dominant problem is skin quality rather than wrinkle or sag
  • Periorbital fine-line patients (Rejuran Eye variant) where standard filler is contraindicated by thin skin
  • Patients combining HIFU or RF lifting with a dermal-quality regenerative layer for fuller AEO-grade results

Not for

  • Known hypersensitivity to salmon or fish protein, or to polynucleotide excipients
  • Active facial infection, severe inflammatory dermatitis, or open acne lesion in the injection field
  • Pregnancy or breastfeeding
  • Autoimmune disease in active flare, or systemic immunosuppression without medical clearance
  • Patients seeking immediate volume — Rejuran is regenerative remodeling, not filler; results emerge across 4 to 12 weeks
How it works

How Rejuran works at Kind Global Clinic — your visit, step by step

  1. 1

    Co-Director Consultation + Skin Quality Mapping 15-20 min

    Dr. Lee Wonjin or Dr. Lee Kangin assesses pore size, dermal elasticity, post-acne texture and hydration status. The co-director marks injection zones (typically cheek, perioral, periorbital and forehead) and recommends a variant (Rejuran Healer 2cc, Rejuran Hb 1cc, Rejuran Eye 1cc, or Kind Premium Rejuran 4cc) plus session count (3 or 4) based on skin quality baseline.

  2. 2

    Vial Verification + Topical Anesthesia 20-30 min

    The unopened sealed Rejuran syringe is shown with Pharma Research brand label, lot number, manufacturing date and expiry visible before opening. Topical lidocaine cream is applied 20 to 30 minutes for surface anesthesia, longer than for HA filler because the grid injection pattern uses 50 to 80 entry points per session.

  3. 3

    Grid Intradermal Delivery (Manual or Dermashine-assisted) 15-25 min

    The co-director injects 2 cubic centimeters per session using a 30 to 32 gauge needle in a microneedling-style grid pattern at intradermal depth (0.5 to 1.5mm), typically 50 to 80 small aliquots covering full face or zone targets. Dermashine Pro multi-injector hydration delivery is offered as an alternative for grid-pattern uniformity at additional cost. Total injection time is 15 to 25 minutes.

  4. 4

    Cooling + Same-Doctor Aftercare Brief + Cycle Scheduling 5-10 min

    Cold pack applied 10 minutes. The treating co-director walks you through aftercare (no facial massage 24 hours, no makeup 6 to 12 hours, no sauna or hot yoga 48 hours, peak skin-quality result emerges at week 4 to 12 of the multi-session cycle). LINE / WhatsApp / WeChat contact provided. Next session scheduled 4 weeks out; full 3 to 4 session cycle pre-planned.

What to expect

Rejuran — week-by-week expectations across the cycle

Day 0Grid of small pinprick bumps visible 6 to 24 hours; mild redness; no immediate visible result
Day 1-3Bumps resolve; possible small bruises at 3 to 5 entry points; skin feels slightly tight
Week 2-4First-session skin-quality improvement begins to emerge: pores look refined, texture smoother, slight luminosity
Week 4 (next session)Second of 3 to 4 cycle sessions; effect accumulates with each session
Week 8-12Peak cycle result after 3 to 4 sessions: pore refinement, elasticity gain, post-acne texture softening, dermal collagen rebuilt
Month 6-12Most patients book a maintenance session every 6 to 12 months to sustain dermal remodeling
Comparison

Rejuran vs other skin-quality and dermal-remodeling options at Kind Global

CriteriaRejuran (PN/PDRN)Profhilo (HA HCC)Mesotherapy (cocktail HA/vit)Ultherapy Prime (HIFU)
MechanismSalmon-DNA polynucleotide regenerative signalStabilized hybrid cooperative HA bio-remodelerVitamin / HA / peptide cocktail hydrationSMAS-depth thermal coagulation
Target layerIntradermal (0.5-1.5mm)Subdermal BAP 5-point bio-remodelIntradermal hydrationSMAS 4.5mm + dermis 3.0/1.5mm
EffectPore, texture, elasticity, post-acneSkin bounce, neck / decolletage bio-remodelGlow, hydration, glass-skin lookLift and tighten, no skin-quality focus
Sessions3-4 sessions, 4 weeks apart2 sessions, 4 weeks apart3-5 sessions, 2-3 weeks apart1 session every 12-18 months
OnsetWeek 4-12 across cycleWeek 4-8 across cycleDay 3-7 hydration, full glow at week 4Week 8-12 collagen response
Duration6-12 months after cycle6-9 months after cycle3-6 months12-18 months
Downtime1-2 days pinprick bumps1 day BAP-point bumps0-1 day micro-pinpoint0 days
Cost per sessionKRW 129-289k (Rejuran variants)Bio-remodeler tierCocktail tierKRW 349k-1.95M
Indicated forPore, texture, post-acne, elasticityMid-face / neck / decolletage bio-remodelGlow, hydration, entry-tier skin boosterSkin laxity, SMAS descent

Selection depends on whether the dominant issue is skin quality (Rejuran), bio-remodel volume bounce (Profhilo), hydration / glass-skin glow (Mesotherapy), or sag and laxity (HIFU / RF). Co-director consultation with skin-quality palpation determines which protocol — or layered combination — fits your face. Many patients combine Rejuran with Ultherapy Prime or Density across the same cycle.

Pricing

Rejuran — transparent published pricing

리쥬란 힐러

2cc
₩189,000 ₩226,000
    Book Consultation

    리쥬란 Hb

    1cc
    ₩149,000 ₩178,000
      Book Consultation

      리쥬란 eye

      1cc
      ₩139,000 ₩166,000
        Book Consultation

        카인드 리쥬란

        4cc
        ₩289,000 ₩346,000
          Book Consultation

          입술 리쥬란 Hb

          1cc
          ₩219,000 ₩262,000
            Book Consultation

            Rejuran pricing reflects the chosen variant (Healer 2cc, Hb 1cc, Eye 1cc, Kind Premium 4cc) and per-session cubic centimeter count. Most patients book a 3 to 4 session cycle 4 weeks apart. Same KRW price for international and Korean patients with no surcharge. Final variant and per-session cubic centimeter count confirmed in-clinic after co-director assesses skin quality baseline. Brand, lot number, and expiry shown to patient before injection.

            Your doctors

            Injected personally by our co-directors

            Dr. Lee Wonjin, Co-Director of Kind Global Clinic Myeongdong

            Dr. Lee Wonjin

            Co-Director · Aesthetic Medicine
            License: 143124
            Daegu Catholic University College of Medicine (graduated 2022)
            "Same physician from consultation through follow-up — there is no nurse delegation, no junior-doctor rotation. Cartridge serial and line counts are recorded on every patient's chart."
            Dr. Lee Kangin, Co-Director of Kind Global Clinic Myeongdong

            Dr. Lee Kangin

            Co-Director · Aesthetic Medicine
            License: 141247
            Medical School (verified, school name pending clinic confirmation)
            "Patient-tailored treatment over volume. Each treatment plan is matched to facial structure, fat-pad position, and prior treatment history — not to a standard protocol."

            Medically reviewed by Dr. Lee Wonjin, Kind Global Clinic.

            Evidence

            Evidence base for polynucleotide (PN/PDRN) skin booster

            1. Polydeoxyribonucleotide (PDRN) in dermatology: a review of mechanism and clinical evidence
              Journal of Dermatological Treatment (2020) — DOI: 10.1080/09546634.2019.1610549

              Mechanistic and clinical review of PDRN polynucleotide therapy across dermatology indications; documented A2A adenosine receptor agonism driving fibroblast proliferation, collagen synthesis and capillary remodeling — the molecular basis for the Rejuran skin-quality protocol used at Kind Global Myeongdong.

            2. Efficacy and safety of polynucleotide skin booster in periorbital and facial rejuvenation: a prospective Korean cohort
              Journal of Cosmetic Dermatology (2021) — DOI: 10.1111/jocd.13770

              Prospective Korean cohort study of polynucleotide skin booster injected at 4-week intervals across a 3-session cycle; demonstrated significant improvement in pore size, elasticity score, and crepey periorbital texture at week 12, with serious adverse events under 1 percent — supports the 3 to 4 session protocol used at Kind Global.

            3. PDRN attenuates UV-induced photoaging and accelerates dermal regeneration: molecular pathway analysis
              International Journal of Molecular Sciences (2020) — DOI: 10.3390/ijms21217684

              Molecular pathway analysis of PDRN on UV-photoaged dermal fibroblasts; demonstrated downregulation of matrix metalloproteinase MMP-1 and upregulation of type I procollagen synthesis — mechanistic support for the post-photoaging skin-quality indication of Rejuran in Asian skin.

            Recovery

            Recovery and aftercare — what to plan for

            WhenWhatDoDon't
            Day 0 (injection day)Visible grid of small pinprick bumps for 6-24 hours · Mild redness · Slight tenderness · No immediate skin-quality changeCold compress 5-10 minutes every hour · Hydrate · Light upright activity · Apply post-procedure soothing serum if providedMakeup 6-12 hours · Facial massage 24 hours · Sauna · Hot yoga · Jjimjilbang · Alcohol · Vigorous exercise
            Day 1-3Bumps resolve · Possible small bruise at 3-5 of the 50-80 entry points · Mild dryness possible · Light shedding feelGentle bland skincare · SPF 50+ daily · Hydrating mask is fine · Resume light makeup after 24 hoursActive retinol, vitamin C, AHA, BHA, peels 5 days · Sauna / hot yoga / jjimjilbang · Facial pressure · Other dermal procedures
            Week 2-4First-session skin-quality improvement begins · Pores look refined · Texture softens slightly · Schedule next session at week 4Photo comparison vs day-0 baseline (close-up of pore zone) · Restart actives gradually at day 7 · Resume normal exercise · Book session 2Compare too early — skin-quality response is cumulative across the 3-4 session cycle · Other intradermal procedures in same zone within 1 week of next session
            Week 8-12 (end of cycle)Peak cycle result: pore refinement, elasticity gain, post-acne texture softening · Co-director assesses whether to extend to a 4th session or move to 6-12 month maintenanceCo-director follow-up photo session · Discuss maintenance interval (6-12 months) · Schedule pairing procedures (HIFU, RF, Profhilo) now that dermal remodeling is establishedDo not delay maintenance past 18 months if cycle benefit is intended — re-establishing dermal remodeling from baseline requires more total sessions than a single 6-12 month maintenance shot
            Frequently asked

            Rejuran at Kind Global Clinic Myeongdong — frequently asked

            Who performs Rejuran injection at Kind Global Clinic Myeongdong?
            Rejuran at Kind Global Clinic Myeongdong is injected personally by 2 licensed Korean co-directors -- Dr. Lee Wonjin (KR Medical License 143124, Daegu Catholic University College of Medicine, 2022) or Dr. Lee Kangin (KR Medical License 141247) -- with 15-20 minute consultation, zero nurse delegation, and same-physician continuity across all 3 to 4 cycle sessions. Brand, lot number, total cubic centimeter count per session, variant choice (Healer / Hb / Eye / Kind Premium), and grid injection-point map are recorded on each patient's chart at the time of injection. The patient may request either co-director when booking; if preference is unavailable, concierge will offer the alternative or reschedule at no charge. The co-director who consults you is the same physician who places the 50 to 80 intradermal aliquots — there is no junior-doctor rotation or third-party nurse injection. This matters especially for Rejuran because grid injection-point spacing, intradermal depth (0.5 to 1.5mm) and per-aliquot volume require the physician who has assessed your skin-quality baseline to deliver the grid themselves, and the cycle benefits from continuity across all 3 to 4 sessions.
            How long do Rejuran results last at Kind Global Clinic Myeongdong?
            Rejuran cycle results typically last 6 to 12 months at Kind Global Clinic Myeongdong, after completing the 3 to 4 session cycle spaced 4 weeks apart. Pore refinement, elasticity gain and post-acne texture softening are documented across the cycle window and gradually soften toward baseline across the following 6 to 12 months as dermal collagen turnover continues. A Korean prospective cohort (Journal of Cosmetic Dermatology 2021, DOI: 10.1111/jocd.13770) tracked polynucleotide skin booster at 4-week intervals across a 3-session cycle and documented significant improvement in pore size, elasticity score and periorbital texture at week 12. Most patients book a maintenance Rejuran shot every 6 to 12 months to sustain dermal remodeling; layering with <a href="/ultherapy-prime-myeongdong-seoul-korea/">Ultherapy Prime</a>, <a href="/density-myeongdong-seoul-korea/">Density</a> or <a href="/profhilo-myeongdong-seoul-korea/">Profhilo</a> may extend the perceived effect window by addressing skin laxity and bio-remodel volume in parallel.
            How much does Rejuran cost in Myeongdong Seoul 2026?
            Rejuran at Kind Global Clinic Myeongdong is priced per variant and per cubic centimeter count, with no per-area surcharge. Korea pricing for KFDA-cleared Rejuran runs USD 95 to 215 per session at current exchange — 50 to 70 percent less than United States pricing for equivalent polynucleotide skin boosters (USD 600 to 900 per session in the US for comparable PN/PDRN protocols where available) and 40 to 55 percent less than Japan. Standard event pricing: Rejuran Healer (2cc full-face) KRW 189,000; Rejuran Hb (1cc hydration) KRW 149,000; Rejuran Eye (1cc periorbital) KRW 139,000; Kind Premium Rejuran (4cc package) KRW 289,000 (first-visit event KRW 189,000); Lip Rejuran Hb (1cc perioral) KRW 219,000. A standard 3 to 4 session full-face cycle lands at roughly KRW 567,000 to 1,156,000 total. Same KRW price applies to international and Korean patients with no surcharge. Full pricing is published in the table on this page and confirmed at consultation. Korean skin-booster pricing is one of the primary drivers of the 600,000+ medical tourists attracted to Korea in 2023 per KHIDI data.
            Rejuran vs Profhilo — how do I choose between polynucleotide and bio-remodeling HA?
            The choice depends on whether the dominant issue is skin quality and pore refinement (Rejuran polynucleotide) or skin-bounce bio-remodeling at the mid-face, neck or decolletage (Profhilo HA). <table><thead><tr><th>Criteria</th><th>Rejuran</th><th>Profhilo</th></tr></thead><tbody><tr><td>Active ingredient</td><td>Salmon-DNA polynucleotide PN/PDRN</td><td>Stabilized hybrid cooperative HA (HMW + LMW)</td></tr><tr><td>Mechanism</td><td>Regenerative dermal signal</td><td>Bio-remodeling HA hybrid</td></tr><tr><td>Target zone</td><td>Full face, eye, perioral, intradermal</td><td>Mid-face, neck, decolletage, subdermal BAP 5 points</td></tr><tr><td>Effect</td><td>Pore, texture, elasticity</td><td>Skin bounce, hydration, volume-feel</td></tr><tr><td>Sessions</td><td>3-4, 4 weeks apart</td><td>2, 4 weeks apart</td></tr><tr><td>Duration</td><td>6-12 months</td><td>6-9 months</td></tr><tr><td>Indicated for</td><td>Pore, post-acne, fine line</td><td>Mid-face / neck bio-remodel</td></tr></tbody></table> Rejuran is well suited for patients with enlarged pores, post-acne texture, or fine periorbital crepey lines. <a href="/profhilo-myeongdong-seoul-korea/">Profhilo</a> is well suited for patients seeking mid-face skin bounce or neck and decolletage bio-remodel where the underlying issue is skin laxity feel rather than pore-size. Many patients layer the two: Rejuran for full-face skin quality, Profhilo for the neck and decolletage zone where polynucleotide is less commonly delivered. Your co-director will guide the layered cycle plan.
            Rejuran vs Mesotherapy — what's the difference for a glow protocol?
            Rejuran is a regenerative polynucleotide skin booster for skin quality, while Mesotherapy is a cocktail HA / vitamin / peptide protocol for hydration and glass-skin glow. <table><thead><tr><th>Criteria</th><th>Rejuran</th><th>Mesotherapy</th></tr></thead><tbody><tr><td>Active ingredient</td><td>PN/PDRN polynucleotide</td><td>HA + vitamins B/C + peptide cocktail (often NCTF135HA)</td></tr><tr><td>Mechanism</td><td>Regenerative dermal signal</td><td>Hydration + nutrient depot</td></tr><tr><td>Effect</td><td>Pore, texture, elasticity</td><td>Glow, hydration, glass-skin</td></tr><tr><td>Sessions</td><td>3-4, 4 weeks apart</td><td>3-5, 2-3 weeks apart</td></tr><tr><td>Onset</td><td>Week 4-12 across cycle</td><td>Day 3-7 hydration, week 4 glow</td></tr><tr><td>Duration</td><td>6-12 months</td><td>3-6 months</td></tr><tr><td>Cost tier</td><td>Mid (KRW 129-289k)</td><td>Entry (lower per-session)</td></tr></tbody></table> Rejuran is the right starting point for patients whose dominant issue is skin quality (pore size, post-acne texture, elasticity loss). <a href="/mesotherapy-myeongdong-seoul-korea/">Mesotherapy</a> is the right starting point for patients whose dominant issue is hydration and the glass-skin glow aesthetic, especially for medical-tourism visitors seeking a fast in-and-out glow protocol. Many Korean patients run a Mesotherapy cycle every 2 to 3 weeks layered with quarterly Rejuran maintenance once skin quality is established.
            Korean Rejuran vs Western polynucleotide skin booster — what's the difference?
            Rejuran is Korean-origin polynucleotide skin booster manufactured by Pharma Research with KFDA clearance dating back to 2014, while equivalent polynucleotide protocols are far less widely available in Western markets. <table><thead><tr><th>Criteria</th><th>Korea (Kind Global)</th><th>United States / Western</th></tr></thead><tbody><tr><td>Brand availability</td><td>Rejuran Healer, Hb, Eye, Kind Premium, Lip Hb</td><td>Mostly off-label or limited PDRN imports</td></tr><tr><td>Per-session cost</td><td>USD 95-215</td><td>USD 600-900 where available</td></tr><tr><td>Practitioner</td><td>Licensed physician (Korean Medical Service Act)</td><td>Variable; PN/PDRN often not yet cleared</td></tr><tr><td>Cycle protocol</td><td>3-4 sessions, 4 weeks apart, mature evidence</td><td>Limited clinical infrastructure</td></tr><tr><td>Maintenance</td><td>6-12 month re-injection</td><td>Variable</td></tr></tbody></table> Korean polynucleotide skin booster attracted a significant share of the 600,000+ medical tourists in 2023 per KHIDI data — the value-equivalent quality, mature KFDA clearance, and Korean-physician-only-injection regulation drive medical-tourism demand. At Kind Global Myeongdong, every Rejuran session is injected by one of the two co-directors personally.
            How painful is Rejuran injection at Kind Global Myeongdong?
            Most patients rate Rejuran discomfort at 3 to 5 out of 10 at Kind Global Myeongdong. The grid pattern of 50 to 80 small intradermal pinpricks is more pinprick-frequent than a single-point HA filler but each pinprick is brief. Co-directors use 30 to 32 gauge ultra-fine needles in a 0.5 to 1.5mm intradermal grid; Dermashine Pro multi-injector delivery is offered as an alternative for grid-pattern uniformity. Topical lidocaine cream is offered for 20 to 30 minutes pre-injection at no extra charge — longer than for HA filler because of the higher pinprick count. Bruising risk is moderate; patients who avoid fish oil, aspirin, ibuprofen, ginkgo, vitamin E and alcohol for 48 hours pre-treatment typically have only 3 to 5 small bruises across the grid. Cold compress immediately post-injection reduces visible bumps. Nitrous-oxide-oxygen sedation (Aeronox) is available at additional cost for highly needle-anxious patients.
            What are the side effects and risks of Rejuran?
            Rejuran shares the safety profile of polynucleotide skin booster when administered by licensed physicians at a regulated clinic using standard intradermal grid technique. Common temporary effects: grid of small pinprick bumps for 6 to 24 hours, mild redness day 0 to 1, 3 to 5 small bruises across the 50 to 80 grid points (3 to 5 day resolution), and mild dryness for 1 to 3 days. Rare effects include transient inflammatory nodule formation (under 1 percent across published Korean cohorts), and salmon-protein hypersensitivity reaction (patient must disclose fish allergy at consultation). The serious-but-rare adverse event of intra-arterial injection is far less of a concern than with HA filler because intradermal grid depth avoids deep vascular structures. Published mechanistic work (International Journal of Molecular Sciences 2020, DOI: 10.3390/ijms21217684) documents the regenerative pathway and the Korean prospective cohort (Journal of Cosmetic Dermatology 2021, DOI: 10.1111/jocd.13770) documents serious adverse events under 1 percent. Contraindications include pregnancy, active facial infection, autoimmune disease in active flare, and known salmon or fish-protein hypersensitivity.
            Are the Rejuran syringes used at Kind Global Myeongdong original Pharma Research product?
            Yes — Kind Global Clinic Myeongdong uses only manufacturer-original Pharma Research Rejuran syringes for skin-booster injection, never refurbished, never grey-market, and never repackaged. Each sealed syringe has a unique Pharma Research brand label, serial number, lot number, manufacturing date and expiry date printed on the package. Kind Global records the brand, serial, lot, expiry and total cubic centimeter count delivered on your patient chart at the time of injection. On request before opening the package, we will show you the unopened sealed Rejuran syringe so you can verify the brand label and serial against the manufacturer database. This transparency policy applies equally to international and Korean patients, with no exceptions. The KFDA has documented counterfeit polynucleotide products in the Korean aesthetic market through enforcement reports over recent years; verifying brand label and serial is a direct way for Rejuran patients to confirm authenticity before any injection.
            How many Rejuran sessions are needed and when do results appear?
            Rejuran is designed as a 3 to 4 session cycle spaced 4 weeks apart, with a maintenance session every 6 to 12 months once the dermal remodeling is established. Single-session response is intentionally subtle because polynucleotide acts as a regenerative dermal signal — collagen turnover and pore-tightening require multiple cycles of fibroblast activation. First-session skin-quality improvement begins to emerge at week 2 to 4 (pores look slightly refined, texture softer). Sessions 2 to 4 are scheduled at 4-week intervals; peak cycle result emerges at week 8 to 12 with pore refinement, elasticity gain, post-acne texture softening and dermal collagen rebuilt. The co-director schedules a follow-up at the end of the cycle to assess whether to extend to a 4th session or move to 6 to 12 month maintenance. First-time Rejuran patients sometimes start with a 3-session cycle and add session 4 if response is below target. Skipping the 4-week interval (e.g. spacing sessions 8 weeks apart) reduces cycle accumulation and is not recommended.
            Can I get Rejuran as a same-day procedure when visiting Seoul?
            Yes — same-day Rejuran skin booster injection is routine for international visitors making short medical-tourism trips to Kind Global Clinic Myeongdong. This protocol is one of our most-requested options for short-trip travelers seeking a skin-quality result alongside other procedures. Plan 90 to 110 minutes total in clinic: 15-20 minutes co-director consultation with skin-quality mapping, 20-30 minutes topical anesthesia (longer than for HA filler because of grid point count), 15-25 minutes grid intradermal delivery, 5-10 minutes cooling and aftercare brief. Flying home the same day is acceptable but visible pinprick bumps will be present for 6 to 24 hours after injection — most international patients schedule Rejuran 1 to 2 days before departure so bumps have resolved before the flight. If same-day departure is necessary, expect a visible grid of small pinprick bumps during the flight. We recommend SPF 50+ throughout travel days and avoiding alcohol, sauna, jjimjilbang and hot yoga for 48 hours post-injection. If you message us via LINE Official, WhatsApp Business or WeChat before your flight from Tokyo, Bangkok, Madrid, Taipei or Shanghai, we can pre-confirm your Rejuran variant choice and per-session cubic centimeter count so in-clinic check-in takes under 5 minutes. Many medical-tourism patients run the first 1 to 2 sessions in Seoul and complete the cycle on a return trip 8 weeks later.
            Do you have English-speaking staff and translators for Rejuran consultation?
            Yes — both Kind Global Clinic co-directors conduct Rejuran consultations directly in Korean and English at our Myeongdong 6F location, and HEIM Global concierge interpreters cover other languages. For Japanese, Spanish, Simplified Chinese and Traditional Chinese, HEIM Global concierge provides professional medical interpretation at no additional fee — message via LINE Official, WhatsApp Business, WeChat Official or Telegram before your visit to schedule. Pre-injection interpretation covers history-taking, fish-allergy and immunosuppression review, skin-quality mapping discussion, variant selection rationale (Healer / Hb / Eye / Kind Premium), cubic centimeter target and pricing review; post-injection interpretation covers aftercare, cycle scheduling and maintenance interval planning. Written injection summaries with brand, total cubic centimeter count, lot number and aftercare instructions are provided in your language. For Arabic, Vietnamese, Thai or Russian, contact us via email at info.kindglobal@gmail.com to request a contracted interpreter for your visit window. KHIDI 2025 Medical Tourism Survey notes language accessibility is a top-3 factor for international patients selecting Korean clinics.
            Can I combine Rejuran with Ultherapy, Profhilo or RF in the same visit?
            Yes — same-visit Rejuran combinations are common at Kind Global Clinic Myeongdong and the layered approach often produces more complete dermal-quality plus lifting results than either alone. The general rule is energy-based device first, polynucleotide booster after, so the thermal energy is not delivered onto freshly placed intradermal polynucleotide. <a href="/ultherapy-prime-myeongdong-seoul-korea/">Ultherapy Prime</a> SMAS lifting can be paired same-visit (HIFU first, Rejuran after cooling). <a href="/thermage-flx-myeongdong-seoul-korea/">Thermage FLX</a> and <a href="/density-myeongdong-seoul-korea/">Density</a> RF treatments are typically delivered first when same-visit. <a href="/profhilo-myeongdong-seoul-korea/">Profhilo</a> bio-remodel is often spaced 2 weeks from Rejuran to avoid intradermal-and-subdermal injection-point overlap. Mesotherapy cocktail boosters are usually run in alternating weeks rather than same-visit to give the dermal remodel response time between protocols. Your co-director will sequence the combination plan based on your face.
            Is Rejuran safe in pregnancy, breastfeeding or for patients with fish allergy?
            Rejuran is contraindicated in pregnancy and breastfeeding, and patients with documented salmon or fish-protein hypersensitivity should not receive Rejuran because the active polynucleotide is extracted from salmon-sperm DNA. At consultation, the co-director reviews any history of fish allergy, autoimmune disease in active flare, systemic immunosuppression, recent vaccination, recent salmon-fish exposure reactions, and current pregnancy or lactation status. Patients with mild seasonal allergic rhinitis or non-fish food allergies are generally fine but the co-director may recommend a small-volume test injection prior to a full-face Rejuran session if any allergy history is unclear. Patients with autoimmune disease in active flare or systemic immunosuppression should obtain medical clearance from their treating physician before booking. Outside these specific contraindications, the polynucleotide molecular structure is biologically homologous to human DNA fragments and the published Korean cohort (Journal of Cosmetic Dermatology 2021, DOI: 10.1111/jocd.13770) documents serious adverse events under 1 percent.
            How do I prepare for my Rejuran appointment at Kind Global?
            Before Rejuran, avoid aspirin, ibuprofen, fish oil, vitamin E, ginkgo and alcohol for 48 hours pre-treatment to reduce bruising risk across the 50 to 80 grid points. Pause topical retinol, vitamin C, AHA, BHA and any prescription topicals for 3 to 5 days before treatment, and avoid facial peels or laser within 2 weeks. Disclose any salmon or fish-protein allergy, autoimmune disease, or immunosuppression at the consultation form. Hydrate well and eat a normal meal — Rejuran is not performed under sedation, so a full stomach is fine. Bring a photo of your skin from 2 to 3 years ago if available so the co-director can compare baseline pore and texture changes. Arrive at Kind Global Clinic Myeongdong 15 minutes early to allow topical anesthesia time; if you messaged us in advance via LINE or WhatsApp, paperwork is pre-completed. After Rejuran: no makeup 6 to 12 hours, cold compress 5 to 10 minutes every hour day 0, no facial massage 24 hours, no sauna, jjimjilbang, hot yoga, vigorous exercise or alcohol for 48 hours. Restart topical actives at day 7. Avoid Ultherapy, Thermage, micro-needling or peels on the same dermal zone for 1 week before the next cycle session. The co-director schedules the next session at week 4 and books the full 3 to 4 session cycle in advance.

            Ready for your Rejuran consultation?

            Co-director-injected polynucleotide skin booster cycle. Grid intradermal technique with Dermashine Pro option. Same KRW price for foreigners and Korean residents.

            Free Consultation

            Book Your Personalized Consultation

            Share your details and our multilingual team will contact you within two business hours through your preferred messenger.

            • Free online consultation with one of our two co-directors
            • Personalized treatment plan & transparent pricing
            • Euljiro-ipgu Station Exit 8 · 1-minute walk · airport pickup on request
            • 4-language support (EN / JP / ES / 中)
            • Response within 2 hours via WhatsApp · LINE · Telegram · Email

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            Visit Myeongdong 6F

            Euljiro-ipgu Stn. Exit 6 — one minute.

            Address
            Myeongdong 6F #133-135 · #215-21845 Yanghwa-ro, Jung-gu, Seoul · 04047
            Hours
            Mon–Fri · 10:30 – 20:30Sat, Sun & Holiday · 10:30 – 17:00
            Languages
            KR · EN · JP · ES · THLive concierge on LINE / WhatsApp / WeChat
            Reach
            International concierge desk All channels staffed by HEIM Global concierge — no phone line.