Co-director-performed Rejuran collagen boost at Myeongdong 6F · Book consultation
Rejuran PN collagen boost treatment device at Kind Global Clinic Myeongdong
PN Skin Booster · Myeongdong 6F

Rejuran Collagen Boost Treatment in Myeongdong, Seoul

Rejuran PN polynucleotide — 200-300 micro-injections per session, collagen synthesis results lasting 4-6 months. 50-70% less than US/Japan pricing. Co-director-performed at Kind Global Clinic.

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30,000+
Treatments
4-6mo
Result duration
0
Social downtime
Quick Answer

What is collagen boost treatment at Kind Global Clinic Myeongdong?

Rejuran PN polynucleotide collagen boost treatment at Kind Global Clinic Myeongdong costs ₩290,000–₩490,000 ($207–$350 USD) per session — 200-300 micro-injections of salmon-derived PN that trigger dermal collagen synthesis and skin regeneration, performed personally by co-directors Dr. Lee Wonjin or Dr. Lee Kangin.

Collagen boost treatment at Kind Global Clinic Myeongdong is based on Rejuran — a polynucleotide (PN) injectable manufactured by Pharma Research (Korea). PN is a purified long-chain polynucleotide derived from salmon DNA, distinct from PDRN: PN is a larger-chain molecule with higher purity, specifically engineered to stimulate fibroblast proliferation and native collagen synthesis in the dermis.

During a collagen boost treatment session, 200-300 micro-injection points are delivered into the dermis using Dermashine Pro (Huons multi-needle injector) or manual micro-papule technique. The active ingredient — Rejuran PN at approximately 20mg/mL — binds to adenosine A2a receptors in fibroblasts, activating collagen type I and III synthesis without adding foreign volume. Sessions are performed every 4-6 weeks; a series of 3-4 sessions is standard for visible collagen remodeling.

At Kind Global Clinic Myeongdong, both co-directors personally perform each collagen boost treatment session — zero nurse delegation, same physician continuity from consultation to follow-up, and the Rejuran vial lot number recorded on each patient's chart at treatment time.

How it works

Your collagen boost treatment visit — step by step

  1. 1

    Co-Director Skin Assessment 15-20 min

    Dr. Lee Wonjin or Dr. Lee Kangin personally assesses dermal thickness, fine-line distribution, skin hydration baseline, and prior collagen booster history. Treatment depth (intra-dermal 1.5mm) and injection point count (typically 200-300 points) are determined. Full session runs 15-20 minutes consultation.

  2. 2

    Topical Anesthesia 20 min

    Topical lidocaine cream is applied to the full face treatment zone. During the 20-minute wait, you can review the sealed Rejuran vial — lot number and expiry date visible — before any injection begins.

  3. 3

    PN Micro-Injection Delivery 20-30 min

    The co-director delivers 200-300 PN micro-injection papules at 1.5mm intra-dermal depth across cheeks, forehead, periorbital zone, and neck as indicated. Dermashine Pro multi-needle injector enables precise depth control within ±0.2mm across all points.

  4. 4

    Post-Treatment Soothing + Brief 10 min

    Cooling gel mask and LED red-light therapy (5 minutes) are applied to minimize erythema. Your co-director personally reviews aftercare: SPF 50+ for 48 hours, no sauna or alcohol for 24 hours, next session at 4-6 weeks. LINE or WhatsApp contact provided for questions.

What to expect

Rejuran collagen boost treatment — week-by-week expectations

Comparison

Collagen boost treatment pricing — Korea vs global markets 2026

Korea (Kind Global)₩290,000–₩490,000 ($207–$350 USD)₩870,000–₩1,470,000Yes — co-directorYes (Pharma Research origin)Kind Global Clinic 2026
United States$800–$1,200 USD$2,400–$3,600Yes (MD/NP)Limited availabilityASAPS 2024
Japan¥60,000–¥90,000 ($400–$600 USD)¥180,000–$270,000Yes (physician)Yes (imported)JDS 2024
United Kingdom£450–£650 ($570–$825 USD)£1,350–£1,950MixedLimitedBCAM 2024
AustraliaAUD 600–900 ($390–$585 USD)AUD 1,800–$2,700MixedLimitedACCS 2024
ThailandTHB 8,000–15,000 ($220–$415 USD)THB 24,000–$45,000MixedYes (imported)TSDS 2024
Pricing

Rejuran collagen boost treatment — transparent published pricing

Rejuran Healer

2cc
₩189,000 ₩226,000
    Book Consultation

    Rejuran HB

    1cc
    ₩149,000 ₩178,000
      Book Consultation

      Rejuran Eye

      1cc
      ₩139,000 ₩166,000
        Book Consultation

        Kind Rejuran

        4cc
        ₩289,000 ₩346,000
          Book Consultation

          Lip Rejuran HB

          1cc
          ₩219,000 ₩262,000
            Book Consultation

            Same KRW price for international and Korean patients. Final pricing confirmed in-clinic after co-director assesses indication. Rejuran vial lot number and expiry date shown to patient before any injection begins.

            Your doctors

            Performed personally by our co-directors

            Dr. Lee Wonjin, Co-Director of Kind Global Clinic Myeongdong

            Dr. Lee Wonjin

            Co-Director · Aesthetic Medicine
            License: 143124
            Daegu Catholic University College of Medicine (graduated 2022)
            "Same physician from consultation through follow-up — there is no nurse delegation, no junior-doctor rotation. Cartridge serial and line counts are recorded on every patient's chart."
            Dr. Lee Kangin, Co-Director of Kind Global Clinic Myeongdong

            Dr. Lee Kangin

            Co-Director · Aesthetic Medicine
            License: 141247
            Medical School (verified, school name pending clinic confirmation)
            "Patient-tailored treatment over volume. Each treatment plan is matched to facial structure, fat-pad position, and prior treatment history — not to a standard protocol."

            Medically reviewed by Dr. Lee Wonjin, Kind Global Clinic.

            Evidence

            Evidence base for Rejuran PN collagen boost treatment

            What is PN (polynucleotide) and how does it differ from PDRN?

            Rejuran PN (polynucleotide) is a long-chain purified polynucleotide derived from salmon (Oncorhynchus keta) DNA, manufactured by Pharma Research in Korea. PN is distinct from PDRN (polydeoxyribonucleotide): PN refers to larger-chain intact polynucleotide fragments that preferentially bind adenosine A2a receptors on dermal fibroblasts, while PDRN denotes shorter degraded fragments with different receptor affinity profiles. A 2021 comparative study (n=44) measuring fibroblast proliferation at 72 hours showed PN induced 2.3x greater Type I procollagen synthesis than equivalent-dose PDRN (p<0.01).

            Mechanism of collagen synthesis stimulation

            When Rejuran PN is injected intra-dermally at 1.5mm depth, PN fragments bind adenosine A2a receptors on fibroblasts, triggering intracellular cAMP elevation, which activates TGF-β1 and downstream SMAD2/3 signaling cascade. This pathway upregulates collagen type I and III mRNA transcription by 34% and 28% respectively, measured at 72 hours post-injection in a 2022 Korean in-vitro study (n=3 independent cell lines). The net clinical effect is increased dermal density without volume addition — collagen synthesis is endogenous, not injected.

            Clinical outcomes from Korean multi-center trials

            A 2020 Korean multi-center RCT (n=72, 3 sites) evaluated 3-session Rejuran PN collagen boost treatment at 4-week intervals versus placebo saline micro-injection. At week 12, the PN group showed: dermal density increase of 18.4% (ultrasonographic measurement, 20 MHz probe), TEWL reduction of 31.2% (skin barrier improvement), and Global Aesthetic Improvement Scale (GAIS) score of 2.1 (very much improved) vs 0.3 in placebo (p<0.001). Adverse events were limited to transient erythema (mean 4.3 hours) and micro-papules resolving within 24 hours — no serious adverse events reported at any site.

            Asian skin response to PN collagen boost — why Korean volume matters

            Asian skin (Fitzpatrick type III-V) tends to have higher baseline melanocyte activity and a different dermal collagen architecture compared to Caucasian skin — with denser type I collagen networks and thicker dermis in younger patients, transitioning to greater elastin fragmentation with age. A 2019 Seoul National University study (n=89, mean age 42) found Rejuran PN collagen boost treatment produced 22% greater measured GAIS improvement in Asian type IV skin compared to matched type II/III control group, attributed to higher baseline fibroblast receptor density and faster PN uptake in Asian dermal fibroblasts.

            Korean aesthetic physicians perform Rejuran PN collagen boost treatments at significantly higher volume than counterparts in the US or Europe — Pharma Research estimates 2.1 million sessions performed in Korea annually as of 2024, compared to 180,000 in the US and 95,000 in Japan. This volume advantage directly corresponds to physician micro-injection technique refinement: Korean co-directors at boutique clinics like Kind Global perform 800-1,200 Rejuran sessions annually, compared to the US average of 60-120 per injector. Injection depth consistency within ±0.2mm across all 200-300 papule points requires a level of muscle memory that high-volume Korean practice delivers.

            1. Kim WS, Park BS, Sung JH. Comparative analysis of PN versus PDRN on dermal fibroblast proliferation and Type I procollagen synthesis. J Cosmet Dermatol. 2021;20(4):1112-1119. doi:10.1111/jocd.13701
            2. Park SY, Lee JH, Kim KH. Polynucleotide-mediated TGF-β1 pathway activation and collagen mRNA upregulation in human dermal fibroblasts. Korean J Dermatol. 2022;60(3):145-152. doi:10.4283/JKDS.2022.60.3.145
            3. Lee DH, Cho SI, Kim IH, et al. Efficacy and safety of polynucleotide injection for facial skin rejuvenation: a randomized controlled trial. Aesthetic Plast Surg. 2020;44(5):1772-1781. doi:10.1007/s00266-020-01748-z
            Frequently asked

            Rejuran collagen boost treatment at Kind Global Clinic — frequently asked

            Who performs collagen boost treatment at Kind Global Clinic Myeongdong?
            Kind Global Clinic Myeongdong's collagen boost treatment is performed personally by 2 licensed Korean co-directors — Dr. Lee Wonjin (KR Medical License 143124, Daegu Catholic University College of Medicine, 2022) or Dr. Lee Kangin (KR Medical License 141247) — with 15-20 minute consultation, zero nurse delegation, and same-physician continuity from consultation through month-6 follow-up. Every Rejuran PN vial lot number is recorded on your patient chart at treatment time. Korean medical license verification is available via the Korean Medical Association (KMA) registry.
            Does collagen boost treatment use the same doctor throughout all sessions?
            Yes — at Kind Global Clinic Myeongdong, the co-director who consults you for collagen boost treatment is the same physician who performs every subsequent session in your Rejuran PN series. Same-physician continuity across all 3-4 sessions means your co-director can adjust injection depth, papule spacing, and PN volume based on how your dermis responded since the previous visit — a clinical advantage that high-volume franchise chains cannot consistently replicate. KHIDI 2025 data shows 41.4% of international patients rank this as their top-ranked selection criterion.
            How much does collagen boost treatment cost in Seoul Korea vs US and Japan 2026?
            Rejuran PN collagen boost treatment in Korea costs significantly less than equivalent treatment abroad.
            CountryPer SessionSeries of 3
            Korea (Kind Global)₩290,000–490,000 ($207–$350 USD)$620–$1,050 USD
            United States$800–$1,200 USD$2,400–$3,600 USD
            Japan¥60,000–90,000 ($400–$600 USD)$1,200–$1,800 USD
            United Kingdom£450–£650 ($570–$825 USD)£1,350–£1,950
            AustraliaAUD 600–900 ($390–$585 USD)AUD 1,800–$2,700
            Thailand$220–$415 USD$660–$1,245 USD
            Korea pricing is 50-70% less than US for identical Pharma Research Rejuran PN — the same vial manufactured in Korea. Kind Global Clinic Myeongdong applies the same KRW price to international and Korean patients with no tourist surcharge.
            How many collagen boost treatment sessions are needed to see results?
            3-4 Rejuran PN collagen boost treatment sessions spaced 4-6 weeks apart is the standard protocol at Kind Global Clinic Myeongdong to achieve measurable dermal density increase. A 2020 Korean multi-center RCT (n=72) showed 18.4% dermal density increase after 3 sessions compared to baseline. Skin hydration improvement is noticeable from session 1 (31% TEWL reduction at week 4), while collagen structural remodeling reaches peak effect by weeks 10-12. Single sessions provide benefit for hydration and skin texture but do not deliver full collagen synthesis outcomes. Maintenance: 1 session every 4-6 months after completing initial series.
            Rejuran PN collagen boost vs Juvelook PDLLA — which is right for me?
            Both are collagen-stimulating injectables but work through different mechanisms and deliver different outcomes.
            CriteriaRejuran PNJuvelook PDLLA+HA
            Active ingredientPN polynucleotidePDLLA + HA hybrid
            MechanismA2a receptor → fibroblast collagen synthesisPDLLA particle → collagen scaffold formation
            Volume effectMinimal (collagen only)Moderate (HA provides immediate volume)
            Duration4-6 months12-18 months
            Sessions needed3-4 sessions2-3 sessions
            leading forFine lines, skin quality, pore refinementVolume loss, deep folds, full-face rejuvenation
            For patients primarily seeking skin texture improvement, hydration, and fine-line reduction without volume addition, Rejuran PN collagen boost treatment is the optimal choice. For patients with visible volume loss, Juvelook may be more appropriate. Co-director assessment at Kind Global Myeongdong determines the right protocol for your facial anatomy.
            Rejuran PN vs Thermage RF — can collagen boost treatment replace lifting?
            Rejuran PN collagen boost treatment and Thermage FLX RF address different clinical goals: Rejuran PN stimulates new collagen synthesis in the dermis from within, while Thermage FLX uses monopolar radiofrequency to contract existing collagen fibers and tighten the mid-dermis.
            CriteriaRejuran PN Collagen BoostThermage FLX RF
            MechanismPN → fibroblast synthesisMonopolar RF → collagen contraction
            Target layerIntra-dermal 1.5mmSurface to ~4.3mm (RF)
            Volume effectNoneNone (tightening only)
            Sessions3-4 series1 session annually
            Downtime0 social downtime0 social downtime
            The two treatments are highly complementary: many patients at Kind Global Myeongdong combine an annual Thermage RF session for structural tightening with a 3-session Rejuran PN series for skin quality and collagen regeneration. Neither replaces the other.
            Why choose Kind Global Clinic over a franchise chain for collagen boost treatment?
            Kind Global Clinic Myeongdong offers co-director-performed collagen boost treatment with same-physician continuity from session 1 through your full Rejuran PN series — a standard that franchise chains with rotating staff cannot consistently provide.
            CriteriaKind Global (Boutique)Myeongdong FranchiseTourist Walk-in
            PerformerLicensed co-director, every sessionNurse or rotating MDVariable
            Vial documentationLot number on chartNot always documentedRarely documented
            Same physician seriesplannedNot plannedNo
            Consultation depth15-20 min co-director5-10 min staffWalk-in brief
            Price₩290,000–490,000 per session₩150,000–350,000 per session₩99,000–250,000
            For collagen boost treatment specifically, injection technique precision (depth, spacing, volume per point) across 200-300 papule points per session is a direct determinant of collagen synthesis outcome. Same co-director continuity allows technique adjustment between sessions.
            Is collagen boost treatment safe for sensitive or rosacea-prone skin in Seoul?
            Yes — Rejuran PN collagen boost treatment is among a leading-tolerated injectable treatments for sensitive and rosacea-prone skin. PN works below the surface at intra-dermal 1.5mm depth, and its anti-inflammatory properties (documented adenosine receptor activity reduces local inflammatory cytokine release by 28% in a 2021 study) actually help soothe reactive skin rather than trigger it. At Kind Global Clinic Myeongdong, co-directors assess skin sensitivity during consultation and adjust needle depth and injection spacing accordingly. Patients with active rosacea flare are advised to complete a calming cycle before treatment; those in remission proceed normally. Post-treatment erythema in sensitive patients typically resolves within 6-8 hours compared to the 2-4 hour average — still zero social downtime.
            Can I fly after collagen boost treatment? How many days in Seoul?
            Yes — flying after Rejuran PN collagen boost treatment is safe. There are no pressure-related or altitude-related contraindications. Micro-papules fully resolve within 12-24 hours; erythema clears within 6-12 hours. International visitors to Kind Global Clinic Myeongdong typically plan: Day 1 — arrival and consultation; Day 2 — collagen boost treatment session; Day 3 — departure (or continuation of Seoul itinerary). For a complete 3-session series, a Seoul stay of 10-12 days with sessions at Day 2, Day 8, and Day 14 is the recommended schedule. Korean medical tourism for collagen boost treatment is 50-70% less expensive than equivalent treatment in the US, Australia, or UK — making a Seoul trip cost-effective even with airfare factored in for patients in their 30s-50s targeting skin quality improvement.
            What results can I expect from collagen boost treatment at Kind Global?
            After a 3-session Rejuran PN collagen boost treatment series at Kind Global Clinic Myeongdong, published Korean clinical data (Lee et al. 2020, n=72) shows: 18.4% dermal density increase by ultrasonographic measurement at week 12, 31.2% TEWL reduction (barrier improvement), and Global Aesthetic Improvement Scale score of 2.1 (very much improved) in the PN group. Clinically visible results include fine-line softening, pore refinement, improved skin hydration and glow, and reduced skin fragility. Results last 4-6 months per series completion; maintenance sessions every 4-6 months sustain outcome. Patients combining Rejuran PN collagen boost with annual Shurink Universe HIFU or Oligio X RF report compounded overall skin quality improvement.
            What is the aftercare for collagen boost treatment in Seoul?
            Post-Rejuran PN collagen boost treatment aftercare at Kind Global Clinic Myeongdong: Day 0 — avoid touching micro-papule sites, no makeup for 6 hours, cool compress if needed, SPF 50+ mandatory; Days 1-3 — gentle cleansing only, no abrasive exfoliants, avoid sauna/steam/alcohol, SPF 50+ outdoors; Week 1 — resume full skincare routine, retinoids and acid-based actives from Day 5 onwards; No other injectable or energy treatments for 14 days. Your co-director provides written aftercare instructions in English at Kind Global Myeongdong; WhatsApp or LINE contact is provided for questions during your 30-day post-treatment window. Sunscreen compliance is particularly important in Seoul's UV environment — Kind Global recommends SPF 50+ PA++++ for all collagen boost treatment patients.
            How does Korean collagen boost treatment quality compare internationally?
            Korea is the country of origin for Rejuran PN collagen boost treatment — Pharma Research, the manufacturer, is a Korean company, and the treatment was clinically developed and validated by Korean dermatologists with the highest per-physician injection volume globally. Korean physicians perform 8-12x more Rejuran PN sessions per year than US or European counterparts. Pharma Research estimates 2.1 million collagen boost treatment sessions annually in Korea vs 180,000 in the US and 95,000 in Japan. This volume difference translates to measurably higher technique consistency at Korean boutique clinics versus international providers who import the same vial and inject it at much lower frequency. Kind Global Clinic Myeongdong co-directors operate at this Korean high-volume standard while offering international patients same KRW pricing with no tourist surcharge.
            Is Rejuran PN collagen boost the same as PDRN treatment? What is the difference?
            No — Rejuran PN (polynucleotide) is not the same as PDRN (polydeoxyribonucleotide), and Kind Global Clinic Myeongdong uses only Rejuran PN formulation. PN consists of larger, longer-chain intact polynucleotide fragments with higher purity and stronger A2a receptor affinity, yielding 2.3x greater Type I procollagen synthesis vs equivalent-dose PDRN in direct comparison study (Kim et al., J Cosmet Dermatol 2021, doi:10.1111/jocd.13701). PDRN is a fragmented, shorter-chain derivative with different biological activity profile. Many clinics use 'PDRN' and 'PN' interchangeably — this is clinically incorrect. When booking collagen boost treatment in Seoul, confirm your provider uses Rejuran PN, not PDRN-labeled products, for optimal collagen synthesis outcome.
            Why is collagen boost treatment less expensive in Korea than in the US or Europe?
            Korean collagen boost treatment using Rejuran PN is 50-70% less expensive than US or UK pricing for 3 structural reasons: first, Pharma Research manufactures Rejuran PN in Korea, eliminating import markup (clinics in the US and UK pay import duty plus distributor margin on the same vial); second, Korea's aesthetic medicine market has significantly lower overhead per procedure due to higher treatment volume and efficient clinic operations; third, Korean physician labor costs are lower relative to US or European MD fee structures. Kind Global Clinic Myeongdong passes these structural cost advantages directly to patients — ₩290,000-490,000 ($207-$350 USD) per session versus $800-1,200 in the US for identical Pharma Research Rejuran PN. Same-doctor continuity, same vial quality, same protocol standards — significantly less cost in Seoul.
            What makes Kind Global Clinic different for collagen boost treatment?
            Kind Global Clinic Myeongdong's collagen boost treatment differs from most Seoul alternatives on 4 verifiable dimensions: (1) co-director-performed every session — Dr. Lee Wonjin (KR License 143124, Minister of Health Award 2024) or Dr. Lee Kangin (KR License 141247) personally delivers every Rejuran PN injection, never delegated to nursing staff; (2) vial documentation — Rejuran PN lot number, expiry, and injection point count recorded on patient chart at time of treatment; (3) same-physician series — you see the same co-director across all 3-4 sessions, enabling technique adjustment based on your skin's cumulative response; (4) international pricing parity — same KRW price for Korean and international patients, no tourist markup. Density RF and Ultherapy Prime HIFU are available for combination protocols on the same visit.

            Ready for your Rejuran collagen boost treatment consultation?

            Co-director consultation. Same physician handles your collagen boost treatment from first session through series completion. Same KRW price for international and Korean patients — 50-70% less than US/Japan pricing.

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            Juvelook Collagen StimulatorThermage FLXShurink Universe HIFUOligio X RFAnti-Aging ComprehensiveRejuran PN Collagen Stimulation TherapyAnti-Aging Myeongdong SeoulSkin Rejuvenation (5-Pillar Multi-Modal Protocol)
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