Who performs Rejuran under-eye injection at Kind Global Clinic Myeongdong?
Rejuran for under eyes at Kind Global Clinic Myeongdong is injected personally by 2 licensed Korean co-directors — Dr. Lee Wonjin (KR Medical License 143124, Daegu Catholic University College of Medicine, 2022) or Dr. Lee Kangin (KR Medical License 141247) — with 15 to 20 minute consultation, zero nurse delegation, and same-physician continuity across all 3 to 4 cycle sessions. Brand, lot number, total cubic centimeter count per session, variant choice (Eye 1cc / Healer 2cc / Hb 1cc) and grid injection-point map are recorded on each patient's chart at the time of injection. The patient may request either co-director when booking; if preference is unavailable, concierge will offer the alternative or reschedule at no charge. The co-director who consults you is the same physician who places the 20 to 40 shallow-intradermal aliquots under the eye — there is no junior-doctor rotation or third-party nurse injection. Periorbital injection requires the physician who assessed your skin-quality baseline to deliver the grid themselves at 0.3 to 0.8mm depth using a 32 to 33 gauge ultra-fine needle.
How long do Rejuran under-eye results last at Kind Global Clinic Myeongdong?
Rejuran Eye cycle results typically last 6 to 12 months at Kind Global Clinic Myeongdong after completing the 3 to 4 session cycle spaced 4 weeks apart. Refinement of crepey under-eye lines, improved dermal density and softened pseudo-dark-circle texture are documented across the cycle window and gradually soften toward baseline across the following 6 to 12 months as dermal collagen turnover continues. A Korean prospective cohort (Journal of Cosmetic Dermatology 2021, DOI: 10.1111/jocd.13770) tracked polynucleotide skin booster at 4-week intervals across a 3-session cycle and documented significant improvement in periorbital crepey-line score, elasticity and pore size at week 12. Most patients book a maintenance Eye 1cc shot every 6 to 12 months; layering with
under-eye filler or
Density may extend the perceived under-eye effect window by addressing volume hollow and skin laxity in parallel.
How much does Rejuran under-eye cost in Myeongdong Seoul 2026?
Rejuran Eye 1cc at Kind Global Clinic Myeongdong is KRW 139,000 ($99 USD) event pricing per session — 50 to 70 percent less than the equivalent polynucleotide periorbital protocol cost in the US ($600 to $900 USD per session where available) and 40 to 55 percent less than Japan. Regular published Eye 1cc price is KRW 166,000 ($119 USD). A standard 3 to 4 session periorbital cycle lands at roughly KRW 417,000 to 556,000 ($298 to $397 USD) total. Same KRW price applies to international and Korean patients with no surcharge. Full pricing is published in the table on this page and confirmed at consultation. Korean periorbital polynucleotide pricing is one of the primary drivers of the 600,000+ medical tourists attracted to Korea in 2023 per KHIDI data.
Rejuran Eye vs under-eye HA filler — which protocol is better for dark circles?
The choice depends on whether the dominant under-eye issue is dermal thinning and crepey-line texture (Rejuran Eye polynucleotide) or volume hollow in the tear-trough plane from fat-pad loss (HA filler).
| Criteria | Rejuran Eye | Under-Eye HA Filler |
|---|
| Mechanism | PN regenerative signal | HA volume in tear-trough plane |
| Target layer | Shallow intradermal 0.3-0.8mm | Supraperiosteal 2-4mm |
| Effect | Crepey lines, texture, dermal density | Tear-trough hollow correction, volume |
| Sessions | 3-4, 4 weeks apart | 1 session, top-up 12-18 months |
| Onset | Week 4-12 across cycle | Same day (volume immediately) |
| Duration | 6-12 months | 12-18 months |
| Cost per session | KRW 139,000 ($99 USD) | KRW 590-790k ($420-565 USD) |
Rejuran Eye is well suited for patients with pseudo-dark-circle texture caused by dermal thinning visibility of underlying vasculature — common in Asian-skin under-eye phenotype.
Under-eye filler is well suited for patients with true volume hollow from fat-pad loss. Many patients layer the two: filler for the tear-trough plane, Rejuran Eye for the overlying skin-quality refinement. Your co-director will guide the layered cycle plan.
Rejuran Eye vs Skinvive for under-eye hydration — what's the difference?
Rejuran Eye is a salmon-DNA polynucleotide regenerative skin booster, while Skinvive is an Allergan microparticulate hyaluronic acid dermal-hydration booster.
| Criteria | Rejuran Eye | Skinvive |
|---|
| Active ingredient | PN polynucleotide (salmon-DNA) | Microparticulate HA |
| Mechanism | Regenerative dermal signal | HA hydration depot |
| Target zone | Periorbital fine lines, dermal density | Full face or periorbital dermal hydration |
| Effect | Crepey lines, pseudo-dark-circle texture | Dermal hydration, fine-line softening |
| Sessions | 3-4, 4 weeks apart | 1-2 sessions, top-up 4-6 months |
| Onset | Week 4-12 across cycle | Week 2-4 hydration |
| Duration | 6-12 months | 4-6 months |
Rejuran Eye is the right starting point for patients whose dominant issue is crepey periorbital lines and dermal thinning. See the dedicated
Rejuran vs Skinvive skin hydration comparison page for full-face context. Many patients run a Skinvive session in advance of a Rejuran Eye cycle for combined hydration plus regenerative remodel.
Korean Rejuran Eye vs Western polynucleotide under-eye protocol — what's the difference?
Rejuran Eye is Korean-origin polynucleotide skin booster manufactured by Pharma Research with KFDA clearance dating back to 2014, while equivalent polynucleotide protocols are far less widely available in Western markets.
| Criteria | Korea (Kind Global) | United States / Western |
|---|
| Brand availability | Rejuran Healer 2cc, Hb 1cc, Eye 1cc, Kind Premium 4cc, Lip Hb 1cc | Mostly off-label or limited PDRN imports |
| Per-session cost | USD 99 per Eye 1cc | USD 600-900 where available |
| Practitioner | Licensed physician (Korean Medical Service Act) | Variable; PN/PDRN often not yet cleared |
| Cycle protocol | 3-4 sessions, 4 weeks apart, mature evidence | Limited clinical infrastructure |
| Maintenance | 6-12 month re-injection | Variable |
Korean polynucleotide skin booster attracted a significant share of the 600,000+ medical tourists in 2023 per KHIDI data — the value-equivalent quality, mature KFDA clearance, and Korean-physician-only injection regulation drive medical-tourism demand. At Kind Global Myeongdong, every Rejuran Eye session is injected by one of the two co-directors personally.
How painful is Rejuran Eye injection at Kind Global Myeongdong?
Most patients rate Rejuran Eye discomfort at 3 to 5 out of 10 at Kind Global Myeongdong. The grid pattern of 20 to 40 shallow-intradermal pinpricks under the eye is more pinprick-frequent than a single-point HA filler but each pinprick is brief and shallow (0.3 to 0.8mm). Co-directors use a 32 to 33 gauge ultra-fine needle in a 20 to 40 point intradermal grid; linear-threading technique may replace grid in thinner-skin patients. Topical lidocaine cream is offered for 20 to 30 minutes pre-injection at no extra charge — longer than for cheek injection because periorbital tolerance is lower. Bruising risk is moderate; patients who avoid fish oil, aspirin, ibuprofen, ginkgo, vitamin E and alcohol for 48 hours pre-treatment typically have only 5 to 8 small bruises across the 20 to 40 points. Cold compress immediately post-injection reduces visible bumps. Nitrous-oxide-oxygen sedation (Aeronox) is available at additional cost for highly needle-anxious patients.
What are the side effects and risks of Rejuran under-eye?
Rejuran Eye shares the safety profile of polynucleotide skin booster when administered by licensed physicians at a regulated clinic using standard shallow-intradermal grid technique. Common temporary effects: grid of 20 to 40 small pinprick bumps under the eye for 4 to 12 hours, mild periorbital redness day 0 to 1, 5 to 8 small bruises across the grid points (3 to 5 day resolution), and mild dryness for 1 to 3 days. Rare effects include transient inflammatory nodule formation (under 1 percent across published Korean cohorts), and salmon-protein hypersensitivity reaction (patient must disclose fish allergy at consultation). The serious-but-rare adverse event of intra-arterial injection is far less of a concern than with HA filler because shallow intradermal grid depth (0.3 to 0.8mm) avoids deep vascular structures. Published mechanistic work (International Journal of Molecular Sciences 2020, DOI: 10.3390/ijms21217684) documents the regenerative pathway and the Korean prospective cohort (Journal of Cosmetic Dermatology 2021, DOI: 10.1111/jocd.13770) documents serious adverse events under 1 percent.
Are the Rejuran Eye syringes at Kind Global Myeongdong original Pharma Research product?
Yes — Kind Global Clinic Myeongdong uses only manufacturer-original Pharma Research Rejuran Eye (Rejuran I) 1cc syringes for periorbital skin-booster injection, never refurbished, never grey-market, and never repackaged. Each sealed syringe has a unique Pharma Research brand label, serial number, lot number, manufacturing date and expiry date printed on the package. Kind Global records the brand, serial, lot, expiry and total cubic centimeter count delivered on your patient chart at the time of injection. On request before opening the package, we will show you the unopened sealed Rejuran Eye syringe so you can verify the brand label and serial against the manufacturer database. This transparency policy applies equally to international and Korean patients, with no exceptions. The KFDA has documented counterfeit polynucleotide products in the Korean aesthetic market through enforcement reports over recent years; verifying brand label and serial is a direct way for Rejuran Eye patients to confirm authenticity before any injection.
How many Rejuran Eye sessions are needed and when do results appear under my eyes?
Rejuran Eye is designed as a 3 to 4 session cycle spaced 4 weeks apart, with a maintenance session every 6 to 12 months once the periorbital dermal remodel is established. Single-session response is intentionally subtle because polynucleotide acts as a regenerative dermal signal — periorbital collagen turnover and crepey-line refinement require multiple cycles of fibroblast activation in the thin under-eye dermis. First-session skin-quality improvement begins to emerge at week 2 to 4 (crepey lines look slightly refined, under-eye dermal texture smoother). Sessions 2 to 4 are scheduled at 4-week intervals; peak cycle result emerges at week 8 to 12 with refinement of crepey under-eye lines, improved dermal density and softened pseudo-dark-circle texture. The co-director schedules a follow-up at the end of the cycle to assess whether to extend to a 4th session or move to 6 to 12 month maintenance. Skipping the 4-week interval (e.g. spacing sessions 8 weeks apart) reduces cycle accumulation and is not recommended.
Can I get Rejuran Eye as a same-day procedure when visiting Seoul?
Yes — same-day Rejuran Eye periorbital injection is routine for international visitors making short medical-tourism trips to Kind Global Clinic Myeongdong. This protocol is one of our most-requested options for short-trip travelers seeking under-eye skin-quality refinement alongside other procedures. Plan 70 to 90 minutes total in clinic: 15-20 minutes co-director consultation with periorbital mapping, 20-30 minutes topical anesthesia, 8-15 minutes shallow-intradermal grid delivery, 5-10 minutes cooling and aftercare brief. Flying home the same day is acceptable but visible pinprick bumps will be present under the eye for 4 to 12 hours after injection — most international patients schedule Rejuran Eye 1 to 2 days before departure so bumps have resolved and concealer is fully effective before the flight. We recommend SPF 50+ throughout travel days and avoiding alcohol, sauna, jjimjilbang and hot yoga for 48 hours post-injection. If you message us via LINE Official, WhatsApp Business or WeChat before your flight from Tokyo, Bangkok, Madrid, Taipei or Shanghai, we can pre-confirm your Rejuran Eye protocol so in-clinic check-in takes under 5 minutes. Many medical-tourism patients run the first 1 to 2 sessions in Seoul and complete the cycle on a return trip 8 weeks later.
Do you have English-speaking staff and translators for Rejuran Eye consultation?
Yes — both Kind Global Clinic co-directors conduct Rejuran Eye consultations directly in Korean and English at our Myeongdong 6F location, and HEIM Global concierge interpreters cover other languages. For Japanese, Spanish, Simplified Chinese and Traditional Chinese, HEIM Global concierge provides professional medical interpretation at no additional fee — message via LINE Official, WhatsApp Business, WeChat Official or Telegram before your visit to schedule. Pre-injection interpretation covers history-taking, fish-allergy and immunosuppression review, periorbital skin-quality mapping discussion, Eye vs Healer variant selection rationale, cubic centimeter target and pricing review; post-injection interpretation covers aftercare, cycle scheduling and maintenance interval planning. Written injection summaries with brand, total cubic centimeter count, lot number and aftercare instructions are provided in your language. KHIDI 2025 Medical Tourism Survey notes language accessibility is a top-3 factor for international patients selecting Korean clinics.
Can I combine Rejuran Eye with under-eye filler, Density or HIFU in the same visit?
Yes — same-visit Rejuran Eye combinations are common at Kind Global Clinic Myeongdong and the layered approach often produces more complete periorbital plus skin-quality results than either alone.
| Combination | Sequencing | Spacing |
|---|
| Rejuran Eye + Under-Eye HA Filler | HA filler first, Rejuran Eye after cooling | Same day or spaced 2 weeks |
| Rejuran Eye + Density RF | Density first, Rejuran Eye after cooling | Same day |
| Rejuran Eye + Ultherapy Prime | HIFU first, Rejuran Eye after cooling | Same day |
| Rejuran Eye + Skinvive | Skinvive first, Rejuran Eye 2 weeks later | Spaced 2 weeks |
| Rejuran Eye + Full-Face Rejuran Healer | Same visit, Healer 2cc then Eye 1cc | Same day |
The general rule is energy-based device first, polynucleotide booster after, so the thermal energy is not delivered onto freshly placed intradermal polynucleotide.
Ultherapy Prime,
Thermage FLX and
Density can all be sequenced before Rejuran Eye.
Under-eye filler is often paired same-visit when both volume and skin-quality are indicated. Your co-director will sequence the combination plan based on your face.
Is Rejuran Eye safe in pregnancy, breastfeeding or for patients with fish allergy?
Rejuran Eye is contraindicated in pregnancy and breastfeeding, and patients with documented salmon or fish-protein hypersensitivity should not receive Rejuran because the active polynucleotide is extracted from salmon-sperm DNA. At consultation, the co-director reviews any history of fish allergy, autoimmune disease in active flare, systemic immunosuppression, recent vaccination, recent salmon-fish exposure reactions, and current pregnancy or lactation status. Patients with mild seasonal allergic rhinitis or non-fish food allergies are generally fine but the co-director may recommend a small-volume test injection prior to a full periorbital Rejuran Eye session if any allergy history is unclear. Patients with autoimmune disease in active flare or systemic immunosuppression should obtain medical clearance from their treating physician before booking. Outside these specific contraindications, the polynucleotide molecular structure is biologically homologous to human DNA fragments and the published Korean cohort (Journal of Cosmetic Dermatology 2021, DOI: 10.1111/jocd.13770) documents serious adverse events under 1 percent.
How do I prepare for my Rejuran Eye appointment at Kind Global?
Before Rejuran Eye, avoid aspirin, ibuprofen, fish oil, vitamin E, ginkgo and alcohol for 48 hours pre-treatment to reduce periorbital bruising risk across the 20 to 40 grid points. Pause topical retinol, vitamin C, AHA, BHA and any prescription topicals around the eye for 3 to 5 days before treatment, and avoid eye-area peels or laser within 2 weeks. Disclose any salmon or fish-protein allergy, autoimmune disease, recent eye-area procedures, or immunosuppression at the consultation form. Hydrate well and eat a normal meal — Rejuran Eye is not performed under sedation. Bring a photo of your under-eye from 2 to 3 years ago if available so the co-director can compare baseline crepey-line and texture changes. Arrive at Kind Global Clinic Myeongdong 15 minutes early to allow topical anesthesia time; if you messaged us in advance via LINE or WhatsApp, paperwork is pre-completed. After Rejuran Eye: no makeup 6 to 12 hours, cold compress 5 minutes every hour day 0, no eye rubbing 48 hours, no sauna, jjimjilbang, hot yoga, vigorous exercise or alcohol for 48 hours. Restart topical actives at day 7. Avoid Ultherapy, Thermage or peels in the periorbital zone for 1 week before the next cycle session. The co-director schedules the next session at week 4 and books the full 3 to 4 session cycle in advance.