Rejuran I Myeongdong Seoul | Kind Global Clinic
Co-director-injected Rejuran I for periorbital fine lines and tear trough at Myeongdong 6F · Book consultation
Rejuran I periorbital polynucleotide skin booster at Kind Global Clinic Myeongdong
Skin Booster · Periorbital Regenerative Injection · Myeongdong 6F

Rejuran I in Myeongdong, Seoul

KFDA-cleared periorbital polynucleotide (PN) skin booster — a thinner Rejuran formulation engineered for tear-trough quality, fine crepey lower-eyelid skin and lateral canthal lines at 1 cubic centimeter per session across a 3 to 4 session cycle 4 weeks apart, injected personally by Dr. Lee Wonjin or Dr. Lee Kangin at Kind Global Clinic.

1cc
Per session, eye zone
3-4
Sessions, 4-wk apart
1-2d
Pinprick downtime
Quick Answer

What is Rejuran I at Kind Global Clinic?

Rejuran I at Kind Global Clinic Myeongdong is a KFDA-cleared periorbital polynucleotide skin booster with a thinner formulation engineered for tear-trough quality, fine lower-eyelid lines and lateral canthal crepey skin, injected at 1cc per session across a 3 to 4 session cycle by our two co-directors.

Rejuran I is the eye-area variant of the Rejuran skin booster family manufactured by Pharma Research in Korea. The active component is purified polynucleotide (PN), a regenerative DNA-fragment signal extracted from salmon-sperm DNA that is biologically homologous to human dermal DNA fragments. Crucially, the I (eye) formulation uses a thinner viscosity than standard Rejuran Healer (2cc full-face) and the Hb variant, because the periorbital skin is the thinnest on the face (about 0.5mm of dermis) and standard-viscosity injectates risk visible nodules or lumpiness in this zone.

The Rejuran I protocol uses 1 cubic centimeter per session, distributed across the periorbital field (lower lid, lateral canthus, infraorbital tear trough region, upper eye lateral skin) as 20 to 30 small intradermal aliquots. Three to four sessions are scheduled 4 weeks apart, with maintenance every 6 to 12 months once dermal remodeling is established. Unlike hyaluronic-acid tear-trough filler, Rejuran I does not add volume — it acts as a regenerative signal that drives fibroblast collagen synthesis, capillary remodeling and extracellular-matrix rebuilding in the thin periorbital dermis.

Both co-directors personally inject every Rejuran I patient — no nurse delegation, no junior-doctor rotation. Brand, lot number, cubic centimeter count, total injection points and 30-32 gauge needle technique are recorded on each patient's chart. Compared with standard <a href="/rejuran-myeongdong-seoul-korea/">Rejuran</a> (2cc full-face for skin quality and pores) or hyaluronic-acid tear-trough filler that adds volume, Rejuran I is the regenerative-only periorbital protocol for patients with thin crepey eyelid skin, fine periorbital lines or who are not yet ready for volumising tear-trough filler. Patients with simultaneous periorbital volume loss may benefit from layering with <a href="/tear-trough-filler-myeongdong-seoul-korea/">Tear Trough Filler</a> at a separate visit.

Who is this for?

Who is Rejuran I for?

For

  • Patients with fine periorbital lines, crepey lower-eyelid skin or lateral canthal texture changes where standard filler is contraindicated by thin skin
  • Late-20s to 50s patients seeking regenerative dermal remodeling around the eye without adding volume
  • Patients with mild infraorbital tear-trough quality issues who are not yet candidates for volumising HA filler
  • Patients combining periorbital quality improvement with full-face Rejuran or with lifting protocols at separate visits
  • Patients with dull, dehydrated periorbital skin and visible dryness lines after extended screen time or sun exposure

Not for

  • Known hypersensitivity to salmon or fish protein, or to polynucleotide excipients
  • Active infection, severe inflammatory dermatitis or open eye-area lesion in the injection field
  • Pregnancy or breastfeeding
  • Autoimmune disease in active flare or systemic immunosuppression without medical clearance
  • Patients seeking immediate volume — Rejuran I is regenerative remodeling, not filler; results emerge across 4 to 12 weeks
How it works

How Rejuran I works at Kind Global Clinic — your visit, step by step

  1. 1

    Co-Director Consultation + Periorbital Mapping 15-20 min

    Dr. Lee Wonjin or Dr. Lee Kangin assesses periorbital skin thickness, lower-lid laxity, infraorbital hollow versus tear-trough quality, lateral canthal lines and prior eye-area treatment history. The co-director marks injection zones (typically lower lid, lateral canthus, infraorbital region, upper eye lateral skin) and confirms Rejuran I (1cc) as the indicated variant versus alternative full-face Rejuran 2cc or eye-area HA filler.

  2. 2

    Vial Verification + Topical Anesthesia 20-30 min

    The unopened sealed Rejuran I syringe is shown with Pharma Research brand label, lot number, manufacturing date and expiry visible before opening. Topical lidocaine cream is applied for 20 to 30 minutes around the eye area for surface anesthesia; the periorbital zone is more sensitive than the cheek, so adequate numbing time is essential before the 20 to 30 entry-point grid pattern begins.

  3. 3

    Periorbital Grid Intradermal Delivery 8-15 min

    The co-director injects 1 cubic centimeter using a 30 to 32 gauge needle at intradermal depth (0.3 to 1.0mm in the thin periorbital dermis), placing 20 to 30 small aliquots covering lower lid, lateral canthus, infraorbital region and upper eye lateral skin. Injection technique is shallower than for the cheek to avoid the orbital septum and visible nodule formation. Total active injection time is 8 to 15 minutes.

  4. 4

    Cooling + Same-Doctor Aftercare Brief + Cycle Scheduling 5-10 min

    Cold pack applied 10 minutes to reduce bruising. The treating co-director walks you through aftercare: no eye rubbing for 24 hours, no eye makeup for 6 to 12 hours, no sauna or hot yoga for 48 hours, SPF 50+ daily and peak skin-quality result emerging at week 4 to 12 of the multi-session cycle. LINE / WhatsApp / WeChat contact provided. Next session scheduled 4 weeks out; full 3 to 4 session cycle pre-planned.

What to expect

Rejuran I — week-by-week expectations across the cycle

Day 0Small pinprick marks at 20 to 30 entry points; mild swelling 2 to 6 hours; possible minor bruising in 10 to 20 percent of patients given periorbital vascularity
Day 1-3Pinpricks fade; any bruising progresses through normal color shift; eye-area swelling resolved; light eye makeup acceptable from day 2
Week 1-2Periorbital skin feels mildly firmer; no visible volume change (Rejuran I is regenerative, not volumising); fibroblast remodeling begins
Week 4First subtle improvement in periorbital texture; finer skin grain; next session delivered if cycle continues
Week 8-12Cumulative dermal remodeling becomes visible; lower-lid crepey skin softens; lateral canthal fine lines less pronounced; co-director chart photo comparison
Month 6-12Sustained periorbital skin quality; maintenance session 6 to 12 months for sustained remodeling; layered <a href="/rejuran-myeongdong-seoul-korea/">Rejuran</a> full-face or HIFU/RF face plan possible at separate visits
Comparison

Rejuran I vs other periorbital and skin-quality protocols at Kind Global

CriteriaRejuran I (eye variant)Rejuran (full-face 2cc)Tear Trough HA FillerEye-Area Botox
MechanismPN polynucleotide regenerative skin booster, thinner formulationPN polynucleotide regenerative skin booster, standard viscosityCross-linked hyaluronic acid volume restorationBotulinum toxin muscle relaxation
TargetPeriorbital fine lines, crepey lid skin, tear-trough qualityFull-face pores, texture, elasticityInfraorbital hollow, volume deficitLateral canthal dynamic wrinkles (crow's feet)
Volume effectNone (regenerative remodeling)None (regenerative remodeling)Yes — adds volume immediatelyNone
Sessions1cc per session, 3-4 sessions 4 wks apart2cc per session, 3-4 sessions 4 wks apart1 session, maintenance every 12-18 mo1 session, maintenance every 3-4 mo
Downtime1-2 day pinprick, possible mild bruising1-2 day pinprick, possible mild bruising1-7 day bruising and swelling possible0-1 day pinprick, possible mild bruising
OnsetWeek 4-12 for skin quality remodelingWeek 4-12 for skin quality remodelingImmediate volumeDay 3-7 muscle relaxation
Indicated forThin crepey eyelid skin without volume deficitPores, texture, elasticity face-wideVolume-deficit tear troughDynamic crow's feet from squinting
Price (per session)KRW 139,000-166,000 (eye 1cc)KRW 189,000-226,000 (Healer 2cc)KRW 350,000-700,000 per syringeKRW 99,000-180,000 per zone

Selection depends on whether the dominant issue is periorbital skin quality (Rejuran I), face-wide skin quality (standard Rejuran), infraorbital volume deficit (HA filler) or dynamic crow's feet (Botox). The four protocols are complementary, not interchangeable. Many patients combine Rejuran I cycles with full-face Rejuran or face-lifting plans at separate visits. Co-director assessment with periorbital mapping determines the right plan for your eye-area profile.

Pricing

Rejuran I — transparent published pricing

Rejuran I (eye 1cc) — Single Session

₩139,000 ₩166,000
    Book Consultation

    Rejuran I 3-session cycle

    ₩397,000 ₩498,000
      Book Consultation

      Rejuran I 4-session cycle

      ₩519,000 ₩664,000
        Book Consultation

        First-visit Rejuran event (full-face 2cc, separate visit)

        ₩129,000 ₩226,000
          Book Consultation

          Rejuran I + full-face Rejuran combined visit (1cc eye + 2cc face)

          ₩319,000 ₩392,000
            Book Consultation

            Rejuran I pricing reflects the periorbital 1cc formulation per session. Same KRW price for international and Korean patients with no surcharge. Final scope confirmed in-clinic after co-director periorbital mapping and Fitzpatrick assessment. Brand, lot and syringe expiry shown to patient before injection.

            Your doctors

            Injected personally by our co-directors

            Dr. Lee Wonjin, Co-Director of Kind Global Clinic Myeongdong

            Dr. Lee Wonjin

            Co-Director · Aesthetic Medicine
            License: 143124
            Daegu Catholic University College of Medicine (graduated 2022)
            "Same physician from consultation through follow-up — there is no nurse delegation, no junior-doctor rotation. Cartridge serial and line counts are recorded on every patient's chart."
            Dr. Lee Kangin, Co-Director of Kind Global Clinic Myeongdong

            Dr. Lee Kangin

            Co-Director · Aesthetic Medicine
            License: 141247
            Medical School (verified, school name pending clinic confirmation)
            "Patient-tailored treatment over volume. Each treatment plan is matched to facial structure, fat-pad position, and prior treatment history — not to a standard protocol."

            Medically reviewed by Dr. Lee Wonjin, Kind Global Clinic.

            Evidence

            Evidence base for polynucleotide periorbital skin booster

            1. Polynucleotide (PN) intradermal skin booster for periorbital skin quality: prospective clinical evaluation
              Journal of Cosmetic Dermatology (2021) — DOI: 10.1111/jocd.13977

              Prospective clinical evaluation of polynucleotide intradermal injection in the periorbital field across multiple sessions 4 weeks apart. Documented significant improvement in fine line score and skin texture grade at week 12 with low adverse-event rate when 30 to 32 gauge needles and intradermal depth were used — evidence base for the Rejuran I periorbital cycle delivered at Kind Global Myeongdong.

            2. Polydeoxyribonucleotide and polynucleotide for facial skin rejuvenation: systematic review
              Dermatologic Surgery (2020) — DOI: 10.1097/DSS.0000000000002264

              Systematic review of PN and PDRN clinical use in facial skin rejuvenation including periorbital applications. Documented mechanism of fibroblast collagen synthesis stimulation, capillary remodeling, and extracellular-matrix rebuilding without volume effect — mechanistic support for the regenerative role of Rejuran I separate from volumising HA filler.

            3. Korean multicenter cohort on intradermal polynucleotide skin booster: safety and efficacy in Asian skin
              Annals of Dermatology (2022) — DOI: 10.5021/ad.2022.34.4.273

              Korean multicenter prospective cohort of intradermal polynucleotide skin booster in Asian Fitzpatrick III to V patients. Demonstrated sustained skin-quality improvement on standardized grading at 12 and 24 weeks, with predominantly mild self-limited pinprick effects and rare bruising in periorbital zones — Korean clinical literature underpinning the Kind Global Rejuran I periorbital protocol.

            Recovery

            Recovery and aftercare — what to plan for

            WhenWhatDoDon't
            Day 0 (injection day)20 to 30 small pinprick marks around the eyes · Mild localized swelling 2 to 6 hours · Possible minor bruising in 10 to 20 percent of patients · No social downtime beyond mild rednessCold pack 10 minutes · Hydrate · Sleep with head slightly elevated for the first night · Light bland skincare around eyes from evening of treatmentRub eyes · Apply eye makeup for 6 to 12 hours · Hot shower, sauna, jjimjilbang, hot yoga, alcohol for 48 hours · Vigorous facial massage
            Day 1-3Pinpricks fade quickly · Any bruising progresses through normal color shift (purple to yellow) · Eye-area swelling resolves · Light eye makeup from day 2Resume normal skincare · SPF 50+ broad-spectrum daily · Continue cold pack if any swelling persists · Soft contact lens use OK if no irritationAggressive eye-area exfoliation · Retinoid in the periorbital field for 5 days · Eyelash extension appointment for 7 days
            Week 1-2Periorbital skin feels mildly firmer · No visible volume change (Rejuran I is regenerative, not volumising) · Fibroblast remodeling begins below the surfaceResume retinoid and serum routine in the periorbital field · Daily SPF 50+ · Drink water consistently · Photograph the eye area for chart comparisonDirect UV without sunscreen · Stack aggressive lasers or peels in the same zone for 14 days · Compare too early — regenerative remodeling is week 4 onwards
            Week 4-12First visible periorbital texture improvement · Lower-lid crepey skin softens · Lateral canthal fine lines less pronounced · Cumulative dermal remodeling continuesCo-director session 2, 3 or 4 as scheduled · Photo comparison · Plan layered full-face <a href="/rejuran-myeongdong-seoul-korea/">Rejuran</a> if face-wide quality is also a concern · Continue SPF 50+ dailySkip sessions of the cycle — dermal remodeling is cumulative · Self-experiment with strong actives in the periorbital field without co-director input · Assume immediate result
            Month 6-12 (maintenance)Sustained periorbital skin quality · Texture and crepey skin softer · Maintenance session every 6 to 12 months recommendedAnnual co-director review · SPF 50+ daily and UV-protective sunglasses outdoors · Photograph quarterly for chart · Plan combined eye + face cycles at separate visits if both concerns persistDiscontinue SPF · Assume permanent change — regenerative cycles require maintenance · Stack new periorbital treatments without co-director sequence guidance
            Frequently asked

            Rejuran I at Kind Global Clinic Myeongdong — frequently asked

            Who performs Rejuran I at Kind Global Clinic Myeongdong?
            Kind Global Clinic Myeongdong's Rejuran I is injected personally by 2 licensed Korean co-directors -- Dr. Lee Wonjin (KR Medical License 143124, Daegu Catholic University College of Medicine, 2022) or Dr. Lee Kangin (KR Medical License 141247) -- with 15 to 20 minute consultation, zero nurse delegation, and same-physician continuity across the 3 to 4 session cycle. Periorbital skin thickness assessment, Fitzpatrick mapping, prior eye-area treatment history, bruising tendency, anticoagulant use and contraindication review are recorded on each patient's chart at the consultation. Patient may request either co-director when booking; if preference is unavailable, concierge will offer the alternative or reschedule at no charge. The co-director who consults you is the same physician who injects the 20 to 30 periorbital aliquots with a 30 to 32 gauge needle, reviews you at session 2, 3 and 4, and runs the photo-comparison follow-up. There is no junior-doctor rotation or third-party nurse application. Brand, lot, syringe expiry and total cubic centimeter count are charted at the time of injection.
            How long do Rejuran I results last at Kind Global Clinic Myeongdong?
            Rejuran I periorbital skin-quality improvement typically holds for 6 to 12 months at Kind Global Clinic Myeongdong after a full 3 to 4 session cycle, with maintenance sessions every 6 to 12 months recommended for sustained dermal remodeling. The polynucleotide signal triggers fibroblast collagen synthesis and capillary remodeling in the thin periorbital dermis, with peak visible benefit at week 8 to 12 after the final session of a cycle. A Korean multicenter cohort study (Annals of Dermatology 2022, DOI: 10.5021/ad.2022.34.4.273) demonstrated sustained skin-quality improvement at 12 and 24 weeks on standardized grading. Result longevity depends on baseline skin quality, sun exposure habits, smoking status, and consistent daily SPF 50+. Hormonal events and prolonged screen exposure can accelerate periorbital aging and shorten the maintenance interval. Some patients layer with <a href="/rejuran-myeongdong-seoul-korea/">Rejuran</a> full-face cycles or with <a href="/ultherapy-prime-myeongdong-seoul-korea/">Ultherapy Prime</a> SMAS lifting at separate visits to extend the duration of overall facial improvement.
            How much does Rejuran I cost in Myeongdong Seoul 2026?
            Rejuran I at Kind Global Clinic Myeongdong starts at KRW 139,000 (approximately USD 100) for a single 1cc periorbital session at event price, scaling to KRW 397,000 (approximately USD 285) for the 3-session starter cycle and KRW 519,000 (approximately USD 371) for the full 4-session cycle. Korea pricing runs 50 to 70 percent less than United States (USD 600 to 1,200 per equivalent periorbital PN/PDRN session at major US dermatology practices) and 35 to 50 percent less than Japan. Standard event pricing: single Rejuran I 1cc session KRW 139,000; 3-session cycle KRW 397,000; 4-session cycle KRW 519,000; combined eye 1cc plus full-face 2cc Rejuran KRW 319,000 per session; first-visit full-face Rejuran event KRW 129,000. Same KRW price applies to international and Korean patients with no surcharge. Final session count typically 3 to 4 confirmed at consultation after periorbital mapping. Korean medical-aesthetic skin-booster pricing is one of the drivers of the 600,000+ medical tourists attracted to Korea in 2023 per KHIDI data.
            Rejuran I vs standard Rejuran (full-face) — which fits my eye area better?
            The eye variant uses a thinner formulation specifically engineered for the periorbital field, while the standard 2cc Healer is sized for full-face skin quality. <table><thead><tr><th>Criteria</th><th>Rejuran I (eye 1cc)</th><th>Rejuran Healer (face 2cc)</th></tr></thead><tbody><tr><td>Formulation</td><td>Thinner viscosity for periorbital skin</td><td>Standard viscosity for face-wide dermis</td></tr><tr><td>Volume per session</td><td>1cc per eye-zone session</td><td>2cc per full-face session</td></tr><tr><td>Target zone</td><td>Lower lid, lateral canthus, tear-trough region</td><td>Cheek, forehead, perioral, full face</td></tr><tr><td>Injection points</td><td>20 to 30 small aliquots</td><td>50 to 80 grid aliquots</td></tr><tr><td>Cycle</td><td>3-4 sessions, 4 weeks apart</td><td>3-4 sessions, 4 weeks apart</td></tr><tr><td>Price (single session)</td><td>KRW 139,000</td><td>KRW 189,000</td></tr></tbody></table> Rejuran I is well suited for patients whose dominant concern is thin crepey lower-lid skin, fine periorbital lines, or tear-trough quality without volume deficit. <a href="/rejuran-myeongdong-seoul-korea/">Rejuran</a> full-face 2cc is well suited for patients whose dominant concern is face-wide pores, texture and elasticity. Many patients run both in parallel at separate visits or on a same-visit combined-session schedule with co-director sequencing.
            Rejuran I vs Tear Trough Filler — which should I choose at Kind Global?
            Rejuran I is regenerative (no immediate volume), while tear-trough HA filler adds immediate volume to the infraorbital hollow. <table><thead><tr><th>Criteria</th><th>Rejuran I</th><th>Tear Trough HA Filler</th></tr></thead><tbody><tr><td>Mechanism</td><td>PN polynucleotide regenerative signal</td><td>Cross-linked hyaluronic acid volume</td></tr><tr><td>Effect</td><td>Skin quality, texture, crepey skin softening</td><td>Volume restoration in infraorbital hollow</td></tr><tr><td>Onset</td><td>Week 4-12 cumulative</td><td>Immediate visible volume</td></tr><tr><td>Duration</td><td>6-12 months with cycle</td><td>12-18 months per syringe</td></tr><tr><td>Downtime</td><td>1-2 day pinprick, mild bruise risk</td><td>1-7 day bruising possible</td></tr><tr><td>Price</td><td>KRW 139k-519k per cycle tier</td><td>KRW 350,000-700,000 per syringe</td></tr></tbody></table> Rejuran I is well suited for patients whose tear-trough issue is skin quality and fine lines rather than true volume loss. <a href="/tear-trough-filler-myeongdong-seoul-korea/">Tear Trough Filler</a> is well suited for patients with a clear volume deficit visible in the infraorbital hollow. Some patients combine Rejuran I for skin quality with HA filler for volume at separate visits, sequenced 2 to 4 weeks apart. Co-director assessment determines whether your tear trough is a quality issue, a volume issue, or both.
            Korean Rejuran I vs Western polynucleotide eye treatments — what's the difference?
            Rejuran is a Korean-origin polynucleotide skin booster manufactured by Pharma Research; equivalent PN and PDRN periorbital products are available in select Western practices but at higher cost and lower physician familiarity. <table><thead><tr><th>Criteria</th><th>Korea (Kind Global)</th><th>United States / Western</th></tr></thead><tbody><tr><td>Product</td><td>Rejuran I (Pharma Research, KFDA-cleared)</td><td>Variable PN/PDRN imports or off-label</td></tr><tr><td>Single-session cost</td><td>USD 100 (KRW 139,000)</td><td>USD 600-1,200 per session</td></tr><tr><td>Application</td><td>Licensed Korean physician (Medical Service Act)</td><td>Physician or extender depending on state</td></tr><tr><td>Cycle frequency</td><td>3-4 sessions, 4 weeks apart, routine</td><td>Variable; often single-session offerings</td></tr><tr><td>Asian skin clinical data</td><td>Korean multicenter cohorts</td><td>Predominantly Caucasian cohort data</td></tr></tbody></table> Korean dermatology has the longest clinical experience with Rejuran because the product is Korean-origin and Korean Society of Dermatology literature spans more than a decade. Korean physician-only application under the Medical Service Act, integrated cycle scheduling, and lower out-of-pocket cost are reasons periorbital skin-booster cycles attract international visitors and contribute to the 600,000+ medical tourists drawn to Korea in 2023 per KHIDI data.
            How painful is Rejuran I at Kind Global Myeongdong?
            Most patients rate Rejuran I discomfort at 3 to 5 out of 10 with topical anesthesia at Kind Global Myeongdong; the periorbital field is more sensitive than the cheek, so adequate numbing time is essential. Topical lidocaine cream is applied for 20 to 30 minutes around the eyes before injection. Each pinprick is brief (1 to 2 seconds) and the full 20 to 30 point grid takes 8 to 15 minutes of active injection. Many patients describe it as quick small pinches rather than sustained pain. Patients with strong bruising history can request additional cold pack or vitamin K cream pre-treatment; nitrous oxide oxygen sedation (Aeronox) is available at additional cost for very anxious patients. Compared with <a href="/rejuran-myeongdong-seoul-korea/">Rejuran</a> full-face 2cc which uses 50 to 80 points, Rejuran I is faster and less cumulative discomfort. Patients on aspirin, ibuprofen, fish oil, vitamin E or ginkgo for 48 hours pre-treatment have a higher bruise risk in the periorbital field; the co-director will recommend pausing these where medically safe.
            What are the side effects and risks of Rejuran I?
            Rejuran I is well-documented as a low-risk regenerative skin booster when injected by licensed physicians. Common temporary effects: 20 to 30 small pinprick marks fading in 24 to 48 hours, mild localized swelling for 2 to 6 hours, minor bruising in 10 to 20 percent of patients given periorbital vascularity (resolves in 5 to 7 days), and brief tenderness on the day of injection. Rare effects include small transient palpable nodules (resolve in 1 to 2 weeks; technique-mitigated with shallow intradermal placement), and very rare hypersensitivity reaction in patients with salmon or fish protein allergy. A prospective clinical evaluation (Journal of Cosmetic Dermatology 2021, DOI: 10.1111/jocd.13977) documented a low adverse-event rate with periorbital PN intradermal use when 30 to 32 gauge needles and intradermal depth were used. Contraindications include known salmon or fish protein allergy, active eye-area infection, severe inflammatory dermatitis in the injection field, pregnancy, breastfeeding, autoimmune disease in active flare and systemic immunosuppression without medical clearance. Your co-director reviews your full medical history at the consultation.
            Is the Rejuran I syringe at Kind Global original Pharma Research?
            Yes — Kind Global Clinic Myeongdong uses only Pharma Research original Rejuran I syringes, never refurbished, never grey-market, never parallel-imported. Each sealed syringe has a unique lot number, manufacturing date and expiry date printed on the package, with the Pharma Research brand label visible. Kind Global records the lot number, total cubic centimeter delivered, total injection points, gauge of needle used, and expiry on your patient chart at the time of injection. On request before injection begins, we will show you the unopened sealed syringe so you can verify the brand and lot against the Pharma Research database. This transparency policy applies equally to international and Korean patients, with no exceptions. Counterfeit skin-booster products have been documented by the KFDA in the Korean aesthetic market through enforcement reports; verifying brand and lot is a direct way patients can confirm authenticity before any injection begins.
            How many Rejuran I sessions are needed and when do results appear?
            The standard Rejuran I protocol is 3 to 4 sessions of 1cc per session, scheduled 4 weeks apart, with the cumulative regenerative effect emerging across weeks 4 to 12 after the final session. Patients with mild periorbital fine lines often see meaningful improvement after the 3-session starter cycle; patients with established crepey lower-lid skin typically need the full 4-session cycle. First subtle texture improvement is visible at week 4; cumulative dermal remodeling becomes clearly visible at week 8 to 12; the full result holds for 6 to 12 months before a maintenance session is recommended. Skipping sessions of the cycle reduces the total polynucleotide signal delivered to the dermis and undermines the regenerative effect — the 4-week spacing exists because each session builds on the prior fibroblast response. Patients hoping for immediate visible change should consider HA filler instead; Rejuran I is regenerative remodeling, not volumising filler. A booster session every 6 to 12 months is recommended for sustained periorbital skin quality.
            Can I get Rejuran I as a same-day procedure when visiting Seoul?
            Yes — same-day Rejuran I session 1 is routine for international visitors at Kind Global Clinic Myeongdong, although the full 3 to 4 session cycle requires return visits to Seoul or coordinated follow-up at a partner clinic abroad. Plan 60 to 90 minutes total in clinic for session 1: 15 to 20 minutes co-director consultation with periorbital mapping, 20 to 30 minutes topical anesthesia, 8 to 15 minutes active injection, 10 minutes cooling and aftercare brief. Flying home the next day is fine — Rejuran I has zero pressure-related contraindication and does not affect ear pressure, sinus, or scalp during flight. We recommend SPF 50+ around the eyes throughout your travel days and UV-protective sunglasses outdoors, and avoiding hot showers, sauna, jjimjilbang, hot yoga, and alcohol for 48 hours. Many medical-tourism patients run sessions 1 and 2 in Seoul on a 4-week return visit and complete sessions 3 and 4 at home with a partner clinic, or schedule a single intensive same-week protocol that compresses the cycle by physician judgement. If you message us via LINE Official, WhatsApp Business or WeChat before your flight from Tokyo, Bangkok, Madrid, Taipei or Shanghai, we can pre-confirm your syringe lot and cycle plan so in-clinic check-in takes under 5 minutes.
            Do you have English-speaking staff and translators for Rejuran I consultation?
            Both Kind Global Clinic co-directors conduct Rejuran I consultations directly in Korean and English at our Myeongdong 6F location. For Japanese, Spanish, Simplified Chinese, and Traditional Chinese, HEIM Global concierge provides professional medical interpretation at no additional fee — message via LINE Official, WhatsApp Business, WeChat Official, or Telegram before your visit to schedule. Pre-treatment interpretation covers periorbital history-taking, allergy review (especially salmon or fish protein), bruising tendency disclosure, anticoagulant use, prior eye-area treatment history, contraindication review and cycle planning. Post-treatment interpretation covers aftercare, the 4-week cycle cadence, SPF and eye-makeup timing, and follow-up scheduling. Written treatment summaries with lot number, cubic centimeter count, gauge and aftercare instructions are provided in your language. For Arabic, Vietnamese, Thai or Russian, contact us via email at info.kindglobal@gmail.com to request a contracted interpreter for your visit window. KHIDI 2025 Medical Tourism Survey notes language accessibility is a top-3 factor for international patients selecting Korean clinics.
            Can I combine Rejuran I with HIFU, RF or eye-area filler in the same visit?
            Sequencing matters for combined eye-area plans at Kind Global Clinic Myeongdong. Rejuran I can be combined with full-face <a href="/rejuran-myeongdong-seoul-korea/">Rejuran</a> in the same visit (eye 1cc plus face 2cc) because both are regenerative polynucleotide. Tear-trough HA filler such as <a href="/tear-trough-filler-myeongdong-seoul-korea/">Tear Trough Filler</a> is typically scheduled at a separate visit 2 to 4 weeks before or after Rejuran I to avoid stacking bruise risk in the same vascular field. HIFU lifting such as <a href="/ultherapy-prime-myeongdong-seoul-korea/">Ultherapy Prime</a> and RF such as <a href="/thermage-flx-myeongdong-seoul-korea/">Thermage FLX</a> are delivered at separate visits, typically before or after the Rejuran I cycle, because energy-device heat into the periorbital field on the same day as fresh injectate is not recommended. Eye-area Botox for dynamic crow's feet can be combined at the same visit if the co-director sequences the Botox first away from the Rejuran injection points. Co-director consultation builds the sequence based on your face profile, downtime tolerance and Seoul visit window.
            Is Rejuran I safe for sensitive eye-area skin or after recent laser?
            Rejuran I is safe for sensitive periorbital skin in most patients when injected by a licensed physician with shallow intradermal technique at Kind Global Myeongdong. Patients with previous strong allergic eye reactions, severe blepharitis, active conjunctivitis or active eye-area dermatitis should defer until the underlying issue is settled. Patients who have had recent periorbital laser (within 4 weeks), recent isotretinoin (within 6 months), recent micro-needling around the eyes (within 2 weeks), or active herpes labialis or zoster outbreak should disclose this at consultation — the co-director may pre-treat with anti-inflammatory protocol, recommend a deferred date, or select a lower-volume approach. Patients with strong bruising tendency, on aspirin, ibuprofen, fish oil, vitamin E or ginkgo should pause these for 48 hours pre-treatment where medically safe. Patients with thin eyelid skin or recent micro-needling may need a 2 to 4 week interval before Rejuran I. Co-director makes the final clinical call based on hands-on assessment and chart review.
            How do I prepare for my Rejuran I appointment at Kind Global?
            Before Rejuran I: avoid aspirin, ibuprofen, fish oil, vitamin E, ginkgo and alcohol for 48 hours pre-treatment to reduce periorbital bruise risk; hydrate well; eat a normal meal (Rejuran I is not performed under sedation, so a full stomach is fine); arrive with clean eye-area skin free of mascara, eyeliner, eye cream and contact lenses. Disclose any salmon or fish protein allergy, anticoagulant or antiplatelet medication, recent isotretinoin, recent periorbital laser, current herpes outbreak, pregnancy and contraception status on the consultation form. Bring sunglasses for the journey home if you bruise easily. Arrive 10 minutes early; if you messaged us in advance via LINE, WhatsApp or WeChat, paperwork is pre-completed. After Rejuran I: cold pack 10 minutes if periorbital swelling persists, sleep with head slightly elevated for the first night, SPF 50+ daily and UV-protective sunglasses outdoors, no eye rubbing 24 hours, no eye makeup 6 to 12 hours, no sauna or hot yoga 48 hours, no aggressive eye-area exfoliation 5 days, no other laser or microneedling around the eyes for 14 days. Photograph the periorbital area at the same lighting and angle every 2 weeks for chart comparison. Follow-up at week 4 for session 2 is pre-booked before you leave the clinic.

            Ready for your Rejuran I consultation?

            Co-director-injected periorbital polynucleotide skin booster cycle. Same physician from consultation through every session. Same KRW price for foreigners and Korean residents.

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