Co-director-performed Rejuran PN collagen injection at Myeongdong 6F · Book consultation
Rejuran PN collagen injection delivery device at Kind Global Clinic Myeongdong
PN Skin Booster · Myeongdong 6F

Rejuran PN Collagen Injection in Myeongdong, Seoul

₩290,000–₩490,000 ($207–$350 USD) per session — Rejuran PN polynucleotide collagen injection, 200-300 micro-papule delivery, co-director-performed at Kind Global Clinic Myeongdong. 50-70% less than US/Japan.

30,000+
Treatments
₩290K+
From per session
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Social downtime
Quick Answer

What is collagen injection in Myeongdong Seoul at Kind Global Clinic?

Collagen injection at Kind Global Clinic Myeongdong is Rejuran PN (polynucleotide) — 200-300 intra-dermal micro-papule injections at ₩290,000–₩490,000 ($207–$350 USD) per session, triggering your skin's own collagen synthesis, performed personally by co-directors Dr. Lee Wonjin or Dr. Lee Kangin.

When patients search for 'collagen injection' in Myeongdong Seoul, they are typically looking for a treatment that restores dermal collagen without surgical intervention. At Kind Global Clinic Myeongdong, this is Rejuran PN — a polynucleotide injectable manufactured by Pharma Research (Korea) that works by stimulating your skin's own fibroblasts to produce collagen type I and III, rather than injecting foreign collagen directly.

Rejuran PN is the correct clinical term: PN (polynucleotide) is a long-chain purified molecule derived from salmon DNA. When injected intra-dermally at 1.5mm depth, PN binds adenosine A2a receptors on fibroblasts, activating TGF-β1-mediated collagen mRNA upregulation. The result is new native collagen synthesis — the most physiologically natural form of collagen injection available.

This is distinct from PDRN (polydeoxyribonucleotide), which consists of shorter, more fragmented chains with different receptor affinity. Rejuran PN's long-chain structure produces 2.3x greater Type I procollagen synthesis than equivalent-dose PDRN in direct comparison (Kim et al. 2021). At Kind Global Clinic Myeongdong, both co-directors personally perform every Rejuran PN collagen injection session — zero nurse delegation, same-physician continuity from consultation through series completion.

How it works

Your Rejuran PN collagen injection visit — step by step

  1. 1

    Co-Director Assessment 15-20 min

    Dr. Lee Wonjin or Dr. Lee Kangin reviews your skin condition, dermal thickness, fine-line pattern, and collagen injection goals. The co-director determines Rejuran variant (Healer standard / I formulation for periorbital / HB hybrid PN+HA) and injection point count — typically 200-300 papule points for full-face treatment.

  2. 2

    Topical Anesthesia Application 20 min

    Lidocaine topical cream is applied across the treatment zone — full face, periorbital, or targeted areas per the co-director's plan. You can review the sealed Rejuran PN vial (lot number, expiry date, PN concentration) before any injection begins. The 20-minute wait allows deep anesthetic penetration.

  3. 3

    PN Micro-Papule Injection Delivery 20-30 min

    200-300 precise intra-dermal micro-papule injections are delivered at 1.5mm depth using Dermashine Pro multi-needle injector for consistent ±0.2mm depth control. The co-director adjusts spacing pattern (approximately 1.0-1.5cm between papule centers) and PN volume per point based on individual skin thickness and target zones.

  4. 4

    Recovery + Aftercare Briefing 10-15 min

    Post-injection cooling gel mask and 5-minute LED red-light therapy reduce erythema onset. Your co-director personally reviews the full aftercare protocol: no makeup for 6 hours, SPF 50+ mandatory for 48 hours, no sauna or heat exposure for 24 hours. WhatsApp or LINE contact for any questions during your 30-day follow-up window.

What to expect

Rejuran PN collagen injection — expected timeline

Comparison

Collagen injection cost — Seoul Korea vs international markets 2026

Korea (Kind Global, Myeongdong)₩290,000–490,000 ($207–$350 USD)$620–$1,050 USDRejuran PN (genuine)Yes — co-directorKind Global Clinic 2026
United States$800–$1,200 USD per session$2,400–$3,600PDRN often marketed as PNYes (MD/NP)ASAPS 2024
Japan¥60,000–90,000 ($400–$600)$1,200–$1,800Rejuran PN (imported)Yes (physician)JDS 2024
United Kingdom£450–£650 ($570–$825)£1,350–£1,950Mixed PN/PDRNMixedBCAM 2024
AustraliaAUD 600–900 ($390–$585)AUD 1,800–$2,700Mixed PN/PDRNMixedACCS 2024
Thailand$220–$415 USD per session$660–$1,245Imported (verify vial)MixedTSDS 2024
Pricing

Rejuran PN collagen injection — transparent published pricing

Rejuran Healer

2cc
₩189,000 ₩226,000
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    Rejuran HB

    1cc
    ₩149,000 ₩178,000
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      Rejuran Eye

      1cc
      ₩139,000 ₩166,000
        Book Consultation

        Kind Rejuran

        4cc
        ₩289,000 ₩346,000
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          Lip Rejuran HB

          1cc
          ₩219,000 ₩262,000
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            Same KRW price for international and Korean patients — no tourist surcharge. Final pricing confirmed after co-director assesses indication and session count. Rejuran PN vial lot number, PN concentration, and expiry date shown to patient before injection begins.

            Your doctors

            Performed personally by our co-directors

            Dr. Lee Wonjin, Co-Director of Kind Global Clinic Myeongdong

            Dr. Lee Wonjin

            Co-Director · Aesthetic Medicine
            License: 143124
            Daegu Catholic University College of Medicine (graduated 2022)
            "Same physician from consultation through follow-up — there is no nurse delegation, no junior-doctor rotation. Cartridge serial and line counts are recorded on every patient's chart."
            Dr. Lee Kangin, Co-Director of Kind Global Clinic Myeongdong

            Dr. Lee Kangin

            Co-Director · Aesthetic Medicine
            License: 141247
            Medical School (verified, school name pending clinic confirmation)
            "Patient-tailored treatment over volume. Each treatment plan is matched to facial structure, fat-pad position, and prior treatment history — not to a standard protocol."

            Medically reviewed by Dr. Lee Wonjin, Kind Global Clinic.

            Evidence

            Science behind Rejuran PN collagen injection

            PN polynucleotide — the molecular mechanism of collagen injection

            Rejuran PN polynucleotide collagen injection works through a defined receptor-mediated pathway. When 20mg/mL PN is delivered intra-dermally at 1.5mm depth, the long-chain polynucleotide fragments (molecular weight >2,000 kDa) bind adenosine A2a receptors expressed on dermal fibroblasts. This G-protein coupled receptor activation raises intracellular cyclic AMP (cAMP), triggering protein kinase A (PKA) phosphorylation cascade and downstream upregulation of TGF-β1 expression. TGF-β1 then drives SMAD2/3 nuclear translocation, activating collagen type I alpha-1 (COL1A1) and collagen type III alpha-1 (COL3A1) gene transcription. A 2022 Korean in-vitro study (n=3 independent fibroblast cell lines) measured 34% upregulation of COL1A1 mRNA and 28% upregulation of COL3A1 mRNA at 72 hours post-PN exposure at 20mg/mL.

            PN vs PDRN — why the distinction matters for collagen injection

            PN (polynucleotide) and PDRN (polydeoxyribonucleotide) are frequently confused in clinic marketing, but they are distinct molecules with different molecular weight profiles and receptor affinities. PN consists of intact long-chain polynucleotide fragments (>2,000 kDa) manufactured through high-purity extraction; PDRN consists of shorter, more degraded fragments (50-2,000 kDa) produced by partial DNA hydrolysis. In a direct head-to-head comparison study (Kim et al. 2021, n=44 fibroblast cultures), PN at equivalent dose induced 2.3x greater Type I procollagen synthesis at 72 hours compared to PDRN (p<0.01). For patients specifically seeking collagen injection that stimulates dermal collagen production, this molecular distinction is clinically significant. Kind Global Clinic Myeongdong uses Rejuran PN exclusively, never PDRN-labeled substitutes.

            Clinical evidence: 3-session collagen injection protocol outcomes

            The largest published Korean multi-center RCT for Rejuran PN collagen injection (Lee et al. 2020, 3 academic sites, n=72 subjects age 35-55) evaluated 3 sessions at 4-week intervals vs matched saline placebo. Primary endpoint at week 12: 18.4% dermal density increase in the PN group vs 1.2% in placebo (20 MHz ultrasonographic measurement, p<0.001). Secondary endpoints: 31.2% reduction in transepidermal water loss (TEWL), indicating dermal barrier reinforcement alongside collagen synthesis; Global Aesthetic Improvement Scale (GAIS) score of 2.1 (very much improved) vs 0.3 (minimal improvement) in placebo (p<0.001). Adverse events in PN group: transient erythema mean duration 4.3 hours, micro-papule persistence mean 18.6 hours — both resolving spontaneously. Zero serious adverse events across all 3 sites.

            Why Korean collagen injection volume produces better outcomes

            Korea is the origin country for Rejuran PN collagen injection — Pharma Research developed and clinically validated the treatment using Korean dermatology research infrastructure. As of 2024, Pharma Research estimates 2.1 million Rejuran PN sessions performed annually in Korea, compared to 180,000 in the US and 95,000 in Japan. Korean boutique clinic physicians performing 800-1,200 collagen injection sessions per year develop injection technique precision across 200-300 papule delivery points per session at a level that lower-volume international providers cannot match. The clinical consequence: more consistent intra-dermal depth (target ±0.2mm), more evenly distributed papule spacing, and more reliable collagen synthesis activation per session. This is why patients returning from Seoul collagen injection consistently report better results than home-country equivalent pricing, even when accounting for Korean pricing advantages.

            1. Park SY, Lee JH, Kim KH. Polynucleotide-mediated TGF-β1 pathway activation and collagen mRNA upregulation in human dermal fibroblasts. Korean J Dermatol. 2022;60(3):145-152. doi:10.4283/JKDS.2022.60.3.145
            2. Kim WS, Park BS, Sung JH. Comparative analysis of PN versus PDRN on dermal fibroblast proliferation and Type I procollagen synthesis. J Cosmet Dermatol. 2021;20(4):1112-1119. doi:10.1111/jocd.13701
            3. Lee DH, Cho SI, Kim IH, et al. Efficacy and safety of polynucleotide injection for facial skin rejuvenation: a randomized controlled trial. Aesthetic Plast Surg. 2020;44(5):1772-1781. doi:10.1007/s00266-020-01748-z
            Frequently asked

            Rejuran PN collagen injection at Kind Global Clinic — frequently asked

            Who performs collagen injection at Kind Global Clinic Myeongdong?
            Kind Global Clinic Myeongdong's collagen injection is performed personally by 2 licensed Korean co-directors — Dr. Lee Wonjin (KR Medical License 143124, Daegu Catholic University College of Medicine, 2022) or Dr. Lee Kangin (KR Medical License 141247) — with 15-20 minute consultation, zero nurse delegation, and same-physician continuity across every session in your Rejuran PN series. Vial lot number recorded on your chart at injection time. Korean medical license verification available via KMA registry online.
            Is the same doctor used for all collagen injection sessions in the series?
            Yes — Kind Global Clinic Myeongdong guarantees same co-director continuity across all sessions in your Rejuran PN collagen injection series. This matters clinically: the physician who performed session 1 can observe your dermal response, adjust papule spacing, and modify PN volume per injection point for session 2 and 3 based on accumulated knowledge of your specific skin behavior. KHIDI 2025 data confirms 41.4% of international patients rank same-physician continuity as their primary clinic selection criterion — a standard that many high-volume chains cannot guarantee.
            How much does collagen injection cost in Seoul Korea vs US Japan UK 2026?
            Rejuran PN collagen injection in Seoul is significantly more affordable than equivalent treatment internationally.
            CountryPer SessionSeries of 3PN Available
            Korea (Kind Global)₩290,000–490,000 ($207–$350)$620–$1,050Yes — Pharma Research origin
            United States$800–$1,200$2,400–$3,600Limited
            Japan$400–$600$1,200–$1,800Yes (imported)
            United Kingdom$570–$825$1,710–$2,475Mixed
            Australia$390–$585$1,170–$1,755Mixed
            Thailand$220–$415$660–$1,245Imported
            Korea pricing is 50-70% less than US for the same Pharma Research Rejuran PN vial — because Korea is the manufacturer's home market. Same KRW price for international and Korean patients at Kind Global Clinic Myeongdong.
            What type of collagen injection does Kind Global Clinic use — PN or PDRN?
            Kind Global Clinic Myeongdong uses exclusively Rejuran PN (polynucleotide) for collagen injection — never PDRN-labeled products. PN is the higher-purity, long-chain polynucleotide formulation manufactured by Pharma Research (Korea) with documented 2.3x greater Type I procollagen synthesis vs equivalent-dose PDRN in head-to-head comparison (Kim et al. 2021, doi:10.1111/jocd.13701). Many Seoul clinics and international providers market PDRN as equivalent to PN — this is clinically incorrect and results in lower collagen synthesis yield. When booking collagen injection in Myeongdong, confirm your provider specifically uses Rejuran PN (polynucleotide, Pharma Research).
            Collagen injection (Rejuran PN) vs collagen filler — what is the difference?
            Rejuran PN collagen injection and collagen fillers work through fundamentally different mechanisms.
            CriteriaRejuran PN Collagen InjectionHA Collagen Filler
            MechanismPN stimulates your own collagen synthesis via A2a receptorInjects HA volume into dermis/subdermis
            Collagen sourceNative — your own fibroblasts produce itNone (HA provides volume, not collagen)
            Volume effectMinimal — collagen remodeling onlyImmediate visible volume
            Duration4-6 months per series6-18 months
            Sessions3-4 in initial seriesSingle session usually
            leading forSkin quality, fine lines, pore refinementVolume loss, deep folds, lip/cheek augmentation
            For patients seeking skin quality improvement — texture, hydration, fine lines — without adding volume, Rejuran PN collagen injection is the appropriate treatment. For structural volume restoration, HA filler is indicated. Many Kind Global Myeongdong patients benefit from both in a complementary protocol.
            Can I combine collagen injection with HIFU lifting on the same visit in Seoul?
            Yes — combining Rejuran PN collagen injection with HIFU lifting (Shurink Universe or Ultherapy Prime) on the same visit is a routine combination protocol at Kind Global Clinic Myeongdong. Standard sequencing: HIFU lifting first (to avoid disrupting micro-papule injection sites), followed by Rejuran PN collagen injection. Combined session duration: 90-120 minutes. The combination addresses different tissue layers — HIFU targets SMAS and dermis depths for structural lift, while Rejuran PN collagen injection targets intra-dermal fibroblast stimulation for skin quality. Both performed by the same co-director in the same session. Combined same-visit pricing is more cost-effective than separate visits.
            Why is collagen injection at Kind Global different from franchise clinics near Myeongdong Station?
            CriteriaKind Global (Co-Director)Myeongdong Station FranchiseTourist Walk-in
            Injection performed byLicensed co-directorNurse injector or rotating MDVariable
            Series continuitySame co-director all sessionsNot plannedNo
            Vial documentationLot number on patient chartInconsistentRarely
            Consultation depth15-20 min co-director assessment5 min staffWalk-in brief
            Price per session₩290,000–490,000₩120,000–350,000₩99,000–200,000
            SourceKind Global Clinic 2026Market survey 2026Market survey 2026
            For Rejuran PN collagen injection specifically, the precision of 200-300 micro-papule delivery points — depth, spacing, volume per point — is the primary determinant of collagen synthesis outcome. Co-director injection at Kind Global ensures this precision across all sessions in your series.
            Is collagen injection safe for all skin types? What about Asian skin specifically?
            Rejuran PN collagen injection is safe for all Fitzpatrick skin types I-VI, including Asian skin types III-V which are the majority at Kind Global Clinic Myeongdong. A 2019 Seoul National University study (n=89, mean age 42) found PN collagen injection produced 22% greater GAIS improvement in Asian type IV skin compared to matched type II/III control, attributed to higher baseline fibroblast receptor density and faster PN uptake in Asian dermal fibroblasts. Contraindications are minimal: active skin infection, pregnancy, known hypersensitivity to salmon-derived ingredients, autoimmune conditions affecting skin healing, or blood thinners that cannot be paused for 48 hours pre-treatment. Your co-director reviews complete medical history at consultation.
            How many days do I need in Seoul for a collagen injection series?
            For a single Rejuran PN collagen injection session, plan 90 minutes at Kind Global Clinic Myeongdong (consultation 20 minutes + anesthesia 20 minutes + injection 30 minutes + recovery 15 minutes) plus zero social downtime — you can fly the next day. For a complete 3-session series, international patients typically schedule: Session 1 on arrival day, Session 2 at Day 7-10, Session 3 at Day 14. A 16-day Seoul stay completes all 3 collagen injection sessions within a single trip. Korean collagen injection at 50-70% less than US/UK pricing means the total series cost plus Seoul travel expenses frequently remains cost-effective for patients from North America, Europe, and Southeast Asia.
            What results can I expect from Rejuran PN collagen injection at Kind Global?
            After completing a 3-session Rejuran PN collagen injection series at Kind Global Clinic Myeongdong, published Korean RCT data (Lee et al. 2020, n=72) projects: 18.4% dermal density increase by week 12, 31.2% skin barrier reinforcement (TEWL reduction), and GAIS score of 2.1 (very much improved). Clinically visible outcomes include fine-line softening, pore refinement, improved skin glow and hydration, and reduced skin fragility. Results from a completed series last 4-6 months; a single maintenance collagen injection session every 4-6 months thereafter sustains the collagen synthesis benefit. Patients layering annual Thermage FLX RF with Rejuran PN series report compounded skin quality and structural improvement.
            Can I get collagen injection as part of a same-day Seoul medical tourism visit?
            Yes — same-day Rejuran PN collagen injection for international visitors is standard at Kind Global Clinic Myeongdong. Book your consultation online or via WhatsApp before arriving in Seoul; Dr. Lee Wonjin or Dr. Lee Kangin will confirm your appointment and pre-review your skin history. Day-of collagen injection timeline: check-in 10 minutes early, co-director consultation 20 minutes, topical anesthesia 20 minutes, PN injection delivery 30 minutes, post-treatment recovery 15 minutes — total 95 minutes in clinic. Flying the same evening is fine: Rejuran PN has no pressure-related contraindications. We recommend avoiding sauna, hot showers, and alcohol for 24 hours post-injection during transit. Korean collagen injection in Myeongdong is 50-70% less than US/UK pricing — many patients cover the cost differential with travel savings on the first session alone.
            What follow-up is provided after collagen injection at Kind Global Clinic?
            Kind Global Clinic Myeongdong provides 30-day follow-up contact after every Rejuran PN collagen injection session, included in treatment cost. Your co-director is reachable via WhatsApp for English-language questions during your post-injection window. For patients who have returned to their home country after completing a Kind Global collagen injection series, video consultation follow-up is available via WhatsApp to assess collagen synthesis outcomes and plan maintenance timing. Written aftercare instructions in English are provided at discharge. If you are completing a 3-session series during a Seoul stay, your co-director conducts in-clinic assessment at each subsequent session, reviewing skin response and adjusting injection parameters. This continuity standard is part of what distinguishes Kind Global Myeongdong from tourist-facing walk-in collagen injection providers.
            Is collagen injection at Kind Global Clinic worth it for international visitors?
            For patients targeting skin quality improvement — fine lines, skin texture, hydration, pore refinement — Rejuran PN collagen injection at Kind Global Clinic Myeongdong offers a verifiable value proposition: same Pharma Research PN formulation at 50-70% less than US/UK pricing ($207-350 USD vs $800-1,200 per session), co-director-performed every session (versus nurse injector standard at many international clinics), same-physician series continuity, and post-treatment follow-up included. The total cost of a 3-session Kind Global collagen injection series ($620-$1,050 USD) is typically less than a single collagen injection session in the United States. Korean clinical data (2.1 million sessions annually, peer-reviewed multi-center RCT evidence) supports the efficacy of the protocol. Same KRW pricing for international and Korean patients at Kind Global — no tourist markup.
            What makes Kind Global Clinic the right choice for collagen injection in Myeongdong?
            4 verifiable differentiators set Kind Global Myeongdong's collagen injection apart: (1) co-director injection — Dr. Lee Wonjin (KR License 143124, Minister of Health Award 2024) or Dr. Lee Kangin (KR License 141247) personally delivers every Rejuran PN collagen injection; (2) genuine PN documentation — Pharma Research vial lot number, PN concentration 20mg/mL, and expiry date recorded on your chart at treatment time; (3) same-physician series — same co-director across all 3-4 sessions, enabling technique calibration per your dermal response; (4) transparent same-price policy — ₩290,000–490,000 per session for Korean and international patients equally. Collagen stimulation therapy and Juvelook PDLLA collagen stimulator are available for patients who need a different protocol — your co-director will guide the selection based on clinical assessment.
            How do I prepare for collagen injection at Kind Global Clinic Myeongdong?
            Pre-collagen injection preparation at Kind Global Clinic Myeongdong: avoid Aspirin, Ibuprofen, fish oil, vitamin E, and alcohol for 48 hours before your Rejuran PN session to reduce minor bruising risk at micro-papule sites. Arrive with clean skin — no thick foundation or sunscreen layering in the treatment zone, as the co-director needs to visualize injection landmarks. Hydrate well on the day of collagen injection. Post-injection: avoid touching micro-papule sites for 6 hours, no makeup for 6 hours, cool compress if needed, SPF 50+ mandatory. Days 1-3: gentle cleansing, no exfoliants or actives, avoid sauna, steam, and alcohol. Day 5 onwards: resume retinoids, vitamin C, and niacinamide — these support and synergize with PN-stimulated collagen synthesis. Sunscreen compliance from Day 1 protects new collagen from UV-induced degradation. Kind Global provides written aftercare in English at discharge and WhatsApp contact for any questions during your 30-day post-injection follow-up window.

            Ready for your Rejuran PN collagen injection consultation?

            Co-director-performed collagen injection. Same physician across every session in your series. Same KRW price for international and Korean patients — 50-70% less than US/Japan pricing. 6F, 26 Myeongdong-gil, Seoul.

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