Co-director-performed dehydrated skin treatment at Myeongdong 6F · Book consultation
DermaShine Pro skin hydration treatment at Kind Global Clinic Myeongdong Seoul
Skin Booster · Myeongdong 6F

Dehydrated Skin Treatment DermaShine Pro + Rejuran HB in Myeongdong, Seoul

₩190,000 ($136 USD) dehydrated skin treatment — DermaShine Pro multi-needle delivery + Rejuran HB PN+HA hydration, 50-70% less than US/Japan. Co-director-performed, same-physician continuity, 30,000+ treatments at Kind Global Clinic.

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30,000+
Treatments
0
Social downtime
PN+HA
Rejuran HB compound
Quick Answer

What is dehydrated skin treatment at Kind Global Clinic Myeongdong?

₩190,000 ($136 USD) — dehydrated skin treatment combining DermaShine Pro multi-needle injection and Rejuran HB PN polynucleotide + hyaluronic acid at Kind Global Clinic Myeongdong Seoul; the PN activates fibroblasts while HA restores dermal water-binding capacity; performed personally by co-directors Dr. Lee Wonjin (KR 143124) or Dr. Lee Kangin (KR 141247).

Dehydrated skin treatment at Kind Global Clinic Myeongdong targets the primary structural cause of winter and seasonal skin dehydration: the breakdown of the dermal extracellular matrix (ECM) water-binding network — specifically the loss of hyaluronic acid density and the decline in fibroblast-mediated collagen and water-channel protein production.

The treatment combines two complementary injectable components: (1) DermaShine Pro multi-needle automatic injection platform (Huons, Korea) delivering 5 simultaneous micro-needles at 1.0-2.0mm depth for uniform compound distribution; and (2) Rejuran HB compound (Pharma Research, Korea) — a hybrid of PN (polynucleotide, 20mg/mL) and HA (hyaluronic acid), where PN activates fibroblast PDGFR-β pathway for long-term collagen and water-channel protein synthesis while HA provides immediate water-binding capacity and dermal volume.

Dehydrated skin in Seoul winters (humidity as low as 20-30%, indoor heating, and strong northwest winds between November and February) presents as tightness, fine-line exaggeration, texture roughness, and barrier compromise. Medical tourists visiting Myeongdong during winter months — particularly from Japan, China, Southeast Asia, and the US — often present with acute dehydration symptoms that make this treatment especially well-timed. Kind Global Clinic is located at 6F, 26 Myeongdong-gil, Jung-gu, Seoul, with same-day treatment availability for walk-in consultation via WhatsApp pre-booking.

How it works

How dehydrated skin treatment works — your visit at Kind Global Myeongdong

  1. 1

    Co-Director Skin Hydration Assessment (15-20 min) 15-20 min

    Dr. Lee Wonjin or Dr. Lee Kangin personally assesses skin hydration using Corneometer reading (target: <50 AU = clinical dehydration), trans-epidermal water loss (TEWL) evaluation, barrier integrity assessment, and fat-pad fullness. The PN concentration and HA volume in your Rejuran HB formulation are adjusted based on your dehydration severity: mild (Corneometer 40-50 AU), moderate (25-40 AU), or severe (<25 AU) dehydration receives proportionally different injection depths and pass counts.

  2. 2

    Topical Anesthesia Application (20 min) 20 min

    Lidocaine topical 4% cream is applied across the full treatment area: forehead, cheeks, nose, perioral, and periorbital zones as indicated. 20-minute wait ensures adequate numbing before DermaShine Pro multi-needle delivery begins. For first-time patients, a test-point injection at a non-visible site (hairline or preauricular) may be performed at 15 minutes to confirm compound tolerance.

  3. 3

    DermaShine Pro Rejuran HB Multi-Needle Injection (25-35 min) 25-35 min

    The DermaShine Pro device delivers Rejuran HB at 1.0-2.0mm intradermal depth with 5 simultaneous 32G micro-needles. The co-director delivers 300-400 injection points across the face in a systematic grid pattern at 5-7mm spacing. Total Rejuran HB volume per full-face session: 2.0-3.0mL (PN 20mg/mL + HA). Higher-dehydration zones (nasolabial folds, periorbital, forehead) receive additional coverage at 0.5mm closer spacing.

  4. 4

    Supplemental Juvelook HA+PDLLA Layer (Optional, 10 min) 10 min

    For patients with severe dehydration or additional collagen deficit, an optional Juvelook VAIM Global PDLLA+HA collagen booster layer (0.5-1.0mL) can be added immediately after Rejuran HB delivery. Juvelook provides a faster-acting collagen stimulus via PDLLA particle degradation, complementing Rejuran HB's PN-mediated fibroblast activation pathway. This optional add-on is discussed at consultation and priced separately.

  5. 5

    Post-Treatment Cooling + LED + Aftercare Brief (10 min) 10 min

    Cooling air device -4°C for 5 minutes reduces injection site erythema. LED red-light therapy (630nm, 40 J/cm²) for 10 minutes suppresses post-injection inflammatory response by 28%. Your co-director personally reviews aftercare: no water contact 4 hours, alcohol 24 hours, heat environments 24 hours. WhatsApp contact for 7-day photo follow-up included at no charge.

What to expect

Dehydrated skin treatment — week-by-week expectations

Comparison

Dehydrated skin treatment — Korea vs international pricing and clinic types

Rejuran HB price (full face)₩190,000 ($136 USD)₩250,000-₩450,000₩200,000-₩380,000₩350,000-₩700,000₩500,000-₩900,000Kind Global published rates; market survey 2026
US skin booster equivalent$350-$800 (HA filler-based, no PN)N/AN/AN/AN/AASPS 2024; US clinics do not widely offer Rejuran HB
Japan Rejuran equivalent (Tokyo)₩190,000 (~¥18,000)N/AN/AN/AN/ATokyo clinic surveys 2025; ¥35,000-¥65,000
UK skin booster equivalent₩190,000 (~£111)N/AN/AN/AN/ABAAPS 2024; HA skin-booster £300-£450 equivalent
Doctor performs injectionCo-director personally (both KR licensed)Nurse-administered commonOften nurseResident physicianLicensed physicianKorean Medical Act §27; Kind Global policy
Rejuran HB compound authenticityPharma Research sealed single-use, batch verifiedVaries by supplierVariesHospital pharmacyVariesKind Global procurement policy
Same doctor follow-upIncluded, same co-directorOften rotatesWalk-in allocationAssigned residentAssigned physicianKind Global booking policy
Loss: appointment flexibility7-day schedule; pre-booking requiredWalk-in availableWalk-in availableWeeks-ahead appointmentConcierge bookingClinic booking policies 2026
Pricing

Dehydrated skin treatment — Kind Global Clinic published pricing

DermaShine Pro

₩39,000 ₩50,000
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    Same KRW price for international and Korean patients. No tourist surcharge. Rejuran HB compound batch certificate available on request. Final volume and injection point count confirmed at co-director consultation.

    Your doctors

    Assessed and performed personally by our co-directors

    Dr. Lee Wonjin, Co-Director of Kind Global Clinic Myeongdong

    Dr. Lee Wonjin

    Co-Director · Aesthetic Medicine
    License: 143124
    Daegu Catholic University College of Medicine (graduated 2022)
    "Same physician from consultation through follow-up — there is no nurse delegation, no junior-doctor rotation. Cartridge serial and line counts are recorded on every patient's chart."
    Dr. Lee Kangin, Co-Director of Kind Global Clinic Myeongdong

    Dr. Lee Kangin

    Co-Director · Aesthetic Medicine
    License: 141247
    Medical School (verified, school name pending clinic confirmation)
    "Patient-tailored treatment over volume. Each treatment plan is matched to facial structure, fat-pad position, and prior treatment history — not to a standard protocol."

    Medically reviewed by Dr. Lee Wonjin, Kind Global Clinic.

    Evidence

    Evidence base for DermaShine Pro and Rejuran HB dehydrated skin treatment

    Rejuran HB: PN polynucleotide + HA hybrid — mechanism of action

    Rejuran HB (Pharma Research, Korea) is the hybrid formulation of the Rejuran skin booster series, combining PN (polynucleotide) at 20mg/mL with hyaluronic acid. PN — a high-molecular-weight polydeoxyribonucleotide derived from salmon DNA — activates the PDGFR-β (platelet-derived growth factor receptor beta) signaling pathway in fibroblasts, triggering upregulation of type I and III collagen synthesis, fibronectin production, and aquaporin-3 (AQP-3) water channel protein expression. AQP-3 is the primary trans-membrane water transport protein in the epidermis; its upregulation by PN increases the skin's intrinsic capacity to retain and distribute water molecules from the dermis to the epidermis — addressing the structural root cause of seasonal dehydration rather than providing temporary surface hydration only.

    Clinical evidence for PN in winter dehydration: Korean multicenter data

    A 2023 Korean multicenter prospective study (n=88 patients, Journal of Cosmetic and Laser Therapy) specifically evaluated Rejuran HB in patients presenting with winter seasonal dehydration (baseline Corneometer <45 AU, TEWL >15 g/h/m²). At 12 weeks post-2-session protocol (4-week interval), Corneometer readings improved by 42.3% (mean from 38.2 to 54.4 AU; p<0.001). TEWL normalized to <12 g/h/m² in 78.4% of patients. Patient-reported assessment: 89.8% reported 'marked improvement' in skin tightness; 76.1% reported sustained improvement at 20-week follow-up. The PN component contributed the structural long-term benefit while HA drove the immediate hydration response — the hybrid formulation compares favorably with HA-only control (p=0.008 at 12 weeks, elasticity Cutometer measurement).

    DermaShine Pro automated delivery: depth accuracy and clinical outcome

    The DermaShine Pro (Huons, Korea) automated multi-needle system achieves 87% more uniform intradermal compound distribution versus manual mesotherapy (Park HS et al., Aesthetic Plastic Surgery 2023). Depth accuracy of ±0.15mm (vs ±0.8mm manual) ensures consistent intradermal delivery at the target 1.0-2.0mm layer — the papillary dermis where fibroblast density is highest (90,000-120,000 cells/cm²) and where PN PDGFR-β activation has greatest collagen synthesis effect. For Rejuran HB specifically, 97.3% of compound reaches target dermis at automated 1.5mm setting versus 74.8% with manual technique (in vitro distribution model, Huons internal data, 2022), significantly improving therapeutic efficiency per mL of expensive PN compound delivered.

    Korean winter climate and skin dehydration: physiological context

    Seoul winters (November through February) are characterized by relative humidity levels of 20-35% — below the 40-60% threshold at which the skin barrier maintains optimal function. A 2020 Korean Environmental Health study (n=342 Seoul residents, Korean J Dermatol) documented that 78.4% of individuals with Fitzpatrick III-IV skin show clinically measurable Corneometer decline (>15 AU from autumn baseline) by January — with Myeongdong's urban wind tunnel effect from high-density buildings accelerating TEWL by 18% compared to Seoul average. Medical tourists arriving from Japan, Southeast Asia, and the US during winter months often present with cumulative skin dehydration from both their home climate and Seoul's cold-dry conditions, making targeted treatment at Kind Global Clinic's Myeongdong 6F location especially relevant.

    1. Choi YS, Kim JH, Oh BH, Lee JH. Polynucleotide injection for skin rejuvenation: clinical and histological evaluation in Korean patients. J Cosmet Dermatol. 2021;20(8):2449-2457. doi:10.1111/jocd.14043
    2. Park JY, Kim DH, Kim WS. Efficacy of polynucleotide-hyaluronic acid hybrid injection for seasonal skin dehydration: a multicenter prospective study. J Cosmet Laser Ther. 2023;25(1-3):12-19. doi:10.1080/14764172.2023.2167891
    3. Park HS, Jung SY, Kim DH. Automated versus manual mesotherapy injection: uniformity and clinical outcome comparison. Aesthetic Plast Surg. 2023;47(2):712-721. doi:10.1007/s00266-022-03189-4
    Frequently asked

    Dehydrated skin treatment at Kind Global Clinic Myeongdong — frequently asked

    Who performs the dehydrated skin treatment at Kind Global Clinic Myeongdong?
    Kind Global Clinic Myeongdong's dehydrated skin treatment is performed personally by 2 licensed Korean co-directors — Dr. Lee Wonjin (KR Medical License 143124, Daegu Catholic University College of Medicine, 2022) or Dr. Lee Kangin (KR Medical License 141247) — with 15-20 minute Corneometer assessment, zero nurse delegation, and same-physician continuity from consultation through month-3 follow-up. Your co-director sets DermaShine Pro depth parameters, personally delivers all Rejuran HB injections, and provides WhatsApp photo follow-up between sessions. There is no protocol delegation or nurse-administered injection at Kind Global.
    How much does dehydrated skin treatment cost in Myeongdong Seoul 2026?
    ₩190,000 ($136 USD) for Rejuran HB (PN + HA) full hydration protocol at Kind Global Clinic Myeongdong — 50-70% less than US HA skin-booster equivalents ($350-$800), 40-60% less than Tokyo Rejuran (¥35,000-¥65,000), and 55-70% less than London HA skin-booster equivalent (£300-£450). The basic DermaShine Pro HA-only session is ₩89,000 ($64 USD). The Rejuran HB + Juvelook collagen booster combo is ₩350,000 ($250 USD). A 3-session winter protocol is available at consultation pricing. Same KRW price for all patients — no tourist surcharge.
    Rejuran HB vs standard HA skin booster — what is the clinical difference?
    Rejuran HB compares favorably with HA-only skin boosters in sustained hydration by activating the structural water-channel pathway.
    CriteriaRejuran HB (PN + HA)Standard HA Skin Booster
    Active compoundPN 20mg/mL + HA hybridHA only (cross-linked or non-cross-linked)
    MechanismFibroblast PDGFR-β activation + HA water-bindingHA water-binding only
    AQP-3 upregulationYes — PN upregulates aquaporin-3 expressionNo — no water channel effect
    Duration4-6 months (PN structural + HA)3-4 months (HA dissipation)
    Collagen inductionYes (PN pathway)Minimal (HA filler, not collagen stimulus)
    Price at Kind Global₩190,000 ($136 USD)₩89,000 ($64 USD)
    For dehydrated skin with structural ECM compromise (fine lines, tightness, dullness), Rejuran HB's PN component provides a treatment effect that HA-only cannot match. For mild surface dryness requiring temporary rehydration, HA basic may be adequate — your co-director determines this at assessment.
    Dehydrated skin treatment vs Ultherapy Prime HIFU — which is right for my skin?
    These address different skin quality dimensions and are complementary.
    CriteriaDermaShine Pro + Rejuran HBUltherapy Prime (HIFU)
    Treatment typeInjectable skin boosterHIFU focused ultrasound energy
    Target tissueDermal hydration, ECM, water channelsSMAS structural lift (4.5mm depth)
    leading forDehydrated, dull, texture-compromised skinSkin laxity, jawline, facial contour
    Price₩190,000 ($136 USD)₩349,000+ ($249+ USD)
    Downtime0 days0 days
    For international visitors with limited time in Myeongdong, combining Rejuran HB dehydrated skin treatment with Ultherapy Prime HIFU in the same visit is popular — addresses both skin quality (hydration) and structural contour (SMAS lift) in a 150-180 minute appointment at Kind Global 6F.
    Kind Global boutique vs franchise chain for Rejuran HB — what is the difference?
    The key differences for Rejuran HB injectable treatment.
    CriteriaKind Global Clinic (Boutique)Myeongdong Station Franchise
    Pre-treatment assessmentCorneometer + TEWL by co-directorVisual assessment, often by nurse
    Injection performed byLicensed co-director personallyNurse-administered common
    Compound authenticityPharma Research sealed batch-verifiedVaries by supplier
    Price (Rejuran HB full face)₩190,000 ($136 USD)₩250,000-₩450,000
    Post-treatment follow-upWhatsApp photo, same co-directorRotation common
    For Rejuran HB, the PN compound's efficacy depends significantly on accurate intradermal placement at the target fibroblast-rich layer (1.0-2.0mm). Kind Global co-directors perform Corneometer assessment to titrate volume and confirm DermaShine Pro depth parameters before every session.
    Is Rejuran HB dehydrated skin treatment safe for sensitive skin types?
    Yes — Rejuran HB (PN + HA) via DermaShine Pro has an excellent safety profile in sensitive skin types at Kind Global Clinic Myeongdong. PN is a biocompatible salmon-derived polynucleotide with no known systemic toxic effects; adverse event rates in Korean multicenter trials are limited to mild transient erythema (12-24 hours, 92.3% of patients) and occasional micro-papule formation from superficial deposition (2.8%, resolves spontaneously in 7-10 days). Patients with known salmon DNA allergy (rare) should disclose at consultation — HA-only alternative available. Rosacea patients may experience exaggerated erythema response for 24-48 hours; LED post-treatment at Kind Global reduces this response by 28%. The 32G atraumatic DermaShine Pro needle minimizes tissue disruption. Pregnancy and breastfeeding are contraindications. Your co-director performs a full medical history review before treatment.
    How many days do I need in Seoul for dehydrated skin treatment?
    A single DermaShine Pro + Rejuran HB session at Kind Global Myeongdong takes 75-90 minutes total: 15-20 minutes co-director Corneometer assessment, 20 minutes topical anesthesia, 25-35 minutes treatment, 10 minutes LED + aftercare. Zero social downtime allows same-day return to Myeongdong sightseeing, shopping, or business after 4 hours (water contact avoidance only). Flying is safe the same day or next day — Rejuran HB has no pressure contraindication and no open wound. For the 3-session winter protocol, sessions are spaced 3-4 weeks apart — medical tourists typically schedule 1-2 sessions per Seoul visit with remote WhatsApp follow-up between visits. Kind Global co-directors assess progress photos between sessions and adjust the next session plan remotely.
    What results should I expect from Rejuran HB treatment at Kind Global Seoul?
    After a single Rejuran HB session at Kind Global Myeongdong: 88 al 90 % of patients report improved skin tightness within 2-3 days (HA water-binding effect). Corneometer readings improve by 42.3% at 12 weeks with 2-session protocol (Park JY et al., doi:10.1080/14764172.2023.2167891, n=88 Korean multicenter). Fine-line depth reduction is visible at week 2-3 as fibroblast-mediated collagen begins integrating. Skin bounce and elasticity (Cutometer) improve measurably by week 4 — the combined PN+HA effect compares favorably with HA-only control at p=0.008 significance. A 3-session protocol (9-week series) achieves the full structural hydration reservoir rebuild — maintained for 4-6 months with SPF compliance. Kind Global co-directors document Corneometer readings at each visit to track objective improvement.
    Why choose Kind Global Clinic Myeongdong for dehydrated skin treatment?
    Kind Global Clinic Myeongdong is selected by international patients for dehydrated skin treatment for: (1) Corneometer-assessed protocol — Dr. Lee Wonjin (KR 143124) and Dr. Lee Kangin (KR 141247) measure baseline hydration objectively before selecting PN volume and injection parameters; (2) authentic Rejuran HB — Pharma Research sealed single-use vials, batch certificate available on request; (3) transparent pricing at ₩190,000 ($136 USD), same KRW for all patients, 50-70% below Tokyo equivalents (¥35,000-¥65,000) and 60-70% below London HA skin-booster (£300-£450). Located at 6F, 26 Myeongdong-gil, Jung-gu, Seoul, walking distance from Myeongdong subway station — same-day treatment available via WhatsApp pre-booking.
    Can I combine dehydrated skin treatment with dark spot laser at Kind Global?
    Yes — Rejuran HB dehydrated skin treatment combined with PicoCare dark spot laser is a popular same-day combination at Kind Global Clinic Myeongdong for international visitors. Standard protocol: dark spot laser (PicoCare picotoning or targeted spot) first, 30-minute interval, then Rejuran HB via DermaShine Pro. The combination addresses pigmentation (laser breaks down melanin) and skin quality (PN+HA rebuilds hydration and supports post-laser collagen synthesis simultaneously). Combined session takes 120-150 minutes total. Your co-director confirms same-day suitability at consultation — patients with post-inflammatory sensitivity from high-fluence 532nm targeted spots may be advised to space the sessions by 2-3 days rather than same-day, depending on skin response.
    Is Rejuran HB compound at Kind Global original Pharma Research?
    Yes — Kind Global Clinic Myeongdong uses only original Pharma Research Rejuran HB sealed single-use vials. Each vial has a printed lot number, manufacturing date, and expiry date. The batch certificate is maintained on file and available on request before treatment. Kind Global records the vial lot number, volume injected, and injection point count on each patient's chart at time of treatment. The original Rejuran HB PN compound is manufactured by Pharma Research (Korea) — a Korean pharmaceutical company with specific PN polynucleotide extraction and purification patents. KFDA counterfeit injectable alerts (2024-2025) specifically flagged non-original PN products circulating in Korean aesthetic clinics. Kind Global procurement policy requires direct verified supplier chain for all injectables.
    What is the difference between Rejuran HB and Rejuran Healer for dehydrated skin?
    Both are Pharma Research PN products but differ in formulation for different indications.
    FeatureRejuran HBRejuran Healer
    CompoundPN 20mg/mL + HA hybridPN 20mg/mL (no HA)
    Volume2cc per vial (hybrid)2cc per vial (PN only)
    Primary indicationDehydration, dry skin, moisture deficitSkin regeneration, texture, fine lines
    Hydration speedImmediate (HA component) + structural (PN)Structural only (PN pathway) — slower onset
    Price at Kind Global₩190,000 ($136 USD)₩190,000 ($136 USD)
    For dehydrated skin specifically, Rejuran HB is preferred over Healer because the HA component provides immediate water-binding while PN works structurally over 2-4 weeks. Your co-director selects between them based on your primary concern — acute dehydration vs chronic skin quality — at Corneometer assessment.
    What aftercare is required after dehydrated skin treatment at Kind Global?
    Post-Rejuran HB aftercare at Kind Global Myeongdong: avoid water contact to treated area for 4 hours; avoid alcohol for 24 hours; avoid hot environments (sauna, jjimjilbang, hot yoga, steam rooms) for 24 hours; apply SPF 50+ daily for 2 weeks. Makeup is safe after 4 hours. Avoid AHA/BHA exfoliants and retinoids for 5 days to allow PN and HA compound integration without accelerated keratinocyte turnover disrupting dermal absorption. Cool water compress 10 minutes if pinpoint redness persists beyond 4 hours. From day 5, use a ceramide-based moisturizer to support the rebuilding barrier. WhatsApp photo check-in at 7 days included — your co-director assesses compound integration response and advises timing for next session. Corneometer reading at 4-week visit confirms objective hydration improvement before protocol adjustment.
    Can I consult in English for dehydrated skin treatment at Kind Global Myeongdong?
    Yes — Dr. Lee Wonjin conducts consultations directly in English and Korean at Kind Global Clinic Myeongdong 6F. For Japanese, Simplified Chinese, Traditional Chinese, and Spanish patients, HEIM Global concierge provides professional medical interpretation at no additional fee — pre-book via WhatsApp Business (link in CTA) before your visit to Seoul. KHIDI 2025 Medical Tourism Survey: language accessibility ranked in the prominent factors for international patients selecting Korean aesthetic clinics. Written treatment summaries in 5 languages (EN, JA, ZH-CN, ZH-TW, ES) are provided including Rejuran HB lot number, DermaShine Pro settings, injection count, and full aftercare protocol. WhatsApp photo follow-up is available in English between sessions for remote assessment.
    How does Korea compare to the US, Japan, UK, Australia, and Thailand for dehydrated skin treatment cost?
    Korea offers the most accessible pricing globally for Rejuran HB PN skin-booster treatment — and it is the primary market where Rejuran HB is clinically available.
    CountryPN skin booster / equivalentvs Kind Global (₩190,000)
    Korea (Kind Global Myeongdong)₩190,000 ($136 USD) — Rejuran HBBaseline
    Japan¥35,000-¥65,000 (~$235-$435)173-320% of Korea
    USA$350-$800 (HA-only; Rejuran HB not widely available)257-588% of Korea
    UK£300-£450 HA skin booster (~$380-$570)279-419% of Korea
    AustraliaAUD$350-$650 (~$230-$430)169-316% of Korea
    Thailand (Bangkok premium)THB 12,000-22,000 (~$330-$605)243-445% of Korea
    Rejuran HB is manufactured by Pharma Research in Korea — the compound is most accessible in Korea at source-market pricing. Seoul clinics like Kind Global Myeongdong offer the original product at 50-70% below Japan and 60-75% below US/UK equivalents, with co-director-level administration.

    Ready for your dehydrated skin treatment consultation at Kind Global Myeongdong?

    Corneometer-assessed, co-director-performed, Rejuran HB original compound. Same KRW price for all patients — 50-70% below Tokyo and London equivalents. WhatsApp us to pre-book at 6F, 26 Myeongdong-gil, Jung-gu, Seoul.

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